Select the ONE answer that is BEST in each question!
1. Which of the following are typical characteristics of an acute leukemia?
Correct!
Wrong!
2 . _____ Myeloid and monocytic
Correct!
Wrong!
3. _____ Monocytic
Correct!
Wrong!
4. _____ Myeloid without maturation
Correct!
Wrong!
5. _____ Lymphoblastic (one cell population)
Correct!
Wrong!
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6. Characteristics of FAB M1 include
Correct!
Wrong!
7. The incidence of FAB M1 is
Correct!
Wrong!
8. _____ A mixture of myeloid and monocytic blasts
Correct!
Wrong!
9. _____ Blasts of the monocytic type
Correct!
Wrong!
10. _____ Many coarsely granular promyelocytes with dumbbell-shaped or bilobed nuclei
Correct!
Wrong!
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11. _____ Myeloblasts, promyelocytes, and myelocytes
Correct!
Wrong!
12. _____ Immature leukocytic and erythrocytic cell types
Correct!
Wrong!
13. _____ Leukemia secondary to Burkitt lymphoma
Correct!
Wrong!
14. _____ Childhood lymphoblastic leukemia
Correct!
Wrong!
15. _____ Older children and adults
Correct!
Wrong!
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16. Chloromas are associated with
Correct!
Wrong!
17. A common characteristic of ALL is
Correct!
Wrong!
18. _____ t(15q+;17q-)
Correct!
Wrong!
19. _____ t(8q-;21q+)
Correct!
Wrong!
20. _____ t(9;22)
Correct!
Wrong!
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21. _____ Sudan black B
Correct!
Wrong!
22. _____ Myeloperoxidase
Correct!
Wrong!
23. _____ PAS
Correct!
Wrong!
24. The Sudan black B cytochemical stain differentiates
Correct!
Wrong!
25. Myeloperoxidase differentiates
Correct!
Wrong!
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26. The PAS reaction is
Correct!
Wrong!
27. Esterase (naphthol AS-D chloracetate) differentiates
Correct!
Wrong!
28. In the nonspecifi c esterase (alpha-naphthyl acetate) staining reaction, the cells of monocytic origin are
Correct!
Wrong!
29. Specifi c nature B-cell surface marker(s) membrane is
Correct!
Wrong!
30. Patients with AML have a good prognosis if
Correct!
Wrong!
Acute Leukemias
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Share your Results:
| 1. Which of the following are typical characteristics of an acute leukemia? A. Replacement of normal marrow elements by leukocytic blasts and bleeding episodes B. Blasts and immature leukocyte forms in the peripheral blood and anemia C. Leukocytosis D. All of the above |
| 2 . _____ Myeloid and monocytic
A. M1 |
| 3. _____ Monocytic
A. M1 |
| 4. _____ Myeloid without maturation
A. M1 |
| 5. _____ Lymphoblastic (one cell population)
A. M1 |
| 6. Characteristics of FAB M1 include A. leukocytosis with maturation of the myeloid cell line in the peripheral blood B. leukocytosis with maturation of the lymphocytic cell line in the peripheral blood C. leukocytosis without maturation of the myeloid cell line in the peripheral blood D. leukocytosis with many mature leukocytes in the peripheral blood |
| 7. The incidence of FAB M1 is A. high in children younger than 18 months of age B. high in children between 1.5 and 12 years of age C. high in middle-aged adults D. both A and C |
| 8. _____ A mixture of myeloid and monocytic blasts
A. FAB M2 |
| 9. _____ Blasts of the monocytic type
A. FAB M2 |
| 10. _____ Many coarsely granular promyelocytes with dumbbell-shaped or bilobed nuclei
A. FAB M2 |
| 11. _____ Myeloblasts, promyelocytes, and myelocytes
A. FAB M2 |
| 12. _____ Immature leukocytic and erythrocytic cell typesA. FAB M2 B. FAB M3 C. FAB M4 D. FAB M6 E. FAB M5 |
| 13. _____ Leukemia secondary to Burkitt lymphoma
A. FAB M1 |
| 14. _____ Childhood lymphoblastic leukemia
A. FAB M1 |
| 15. _____ Older children and adults
A. FAB M1 |
| 16. Chloromas are associated with A. FAB M1 B. FAB M3 C. FAB M4 D. FAB M5 |
| 17. A common characteristic of ALL is A. bone and joint pain B. many blast cells with Auer rodsC. leukocytopenia D. a leukemia of older persons |
| 18. _____ t(15q+;17q-)
A. FAB M2 |
| 19. _____ t(8q-;21q+)
A. FAB M2 |
| 20. _____ t(9;22)
A. FAB M2 |
| 21. _____ Sudan black B
A. Glycogen |
| 22. _____ Myeloperoxidase
A. Glycogen |
| 23. _____ PAS
A. Glycogen |
| 24. The Sudan black B cytochemical stain differentiates A. acute myeloid from ALL B. acute monocytic from AML C. myeloid leukemia from a leukemoid reaction D. acute myeloid from acute myelomonocytic leukemia |
| 25. Myeloperoxidase differentiates A. acute myeloid from chronic myelocytic leukemia B. acute myeloid and acute monocytic from ALL C. acute myelomonocytic from acute monocytic leukemia D. acute lymphoblastic from acute monocytic leukemia |
| 26. The PAS reaction is A. positive in the neutrophilic granulocytes, except blasts B. positive in a block-like pattern in some lymphoblasts C. negative in megakaryoblasts D. negative in myelocytes |
| 27. Esterase (naphthol AS-D chloracetate) differentiates A. granulocytic (promyelocytic to segmented neutrophils) from the monocytic cell line B. promyelocytes from myelocytes C. monoblasts from myeloblasts D. metamyelocytes from myelocytes |
| 28. In the nonspecifi c esterase (alpha-naphthyl acetate) staining reaction, the cells of monocytic origin are A. strongly positive B. positive initially and positive after sodium fluoride incubation C. positive initially and negative after sodium fluoride incubation D. negative |
| 29. Specifi c nature B-cell surface marker(s) membrane is A. CD 79a B. CD19 C. CD 20 D. all of the above |
| 30. Patients with AML have a good prognosis if A. Less than 45 years of age B. Over rods are present in blast cells C. Ph chromosome D. all of the above |
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