[Immunology] The Transplantation Immunology Quizzes (8 tests)

The type of allograft rejection associated with vascular and parenchymal injury with lymphocyte infiltrates is which of the following?

Hyperacute rejection

Acute cellular rejection

Acute humoral rejection

Chronic rejection

Correct! Wrong!

Antigen receptors on T lymphocytes bind HLA class II molecules with the help of which accessory molecule?

CD2

CD3

CD4

CD8

Correct! Wrong!

Patients at risk for graft-versus-host disease (GVHD) include each of the following, except recipients of

bone marrow transplants.

lung transplants.

liver transplants.

irradiated leukocytes.

Correct! Wrong!

HLA molecules exhibit all of the following properties, except that they

belong to the immunoglobulin superfamily.

are heterodimeric.

are integral cell membrane glycoproteins.

are monomorphic.

Correct! Wrong!

Kidney allograft loss from intravascular thrombosis without cellular infiltration 5 days post-transplant raises the suspicion level about which primary rejection mechanism?

Hyperacute rejection

Accelerated humoral rejection

Acute humoral rejection

Acute cellular rejection

Correct! Wrong!

Which reagents would be used in a direct (forward) donor–recipient crossmatch test?

Donor serum and recipient lymphocytes rabbit serum complement

Recipient serum and donor lymphocytes rabbit serum complement

Donor stimulator cells recipient responder cells complete culture medium

Recipient stimulator cells donor responder cells complete culture medium

Correct! Wrong!

The indirect allorecognition pathway involves which one of the following mechanisms?

Processed peptides from polymorphic donor proteins restricted by recipient HLA class II molecules

Processed peptides from polymorphic recipient proteins restricted by donor HLA class I molecules

Intact polymorphic donor protein molecules recognized by recipient HLA class I molecules

Intact polymorphic donor protein molecules recognized by recipient HLA class II molecules

Correct! Wrong!

Which immunosuppressive agent selectively inhibits IL-2 receptor-mediated activation of T cells and causes clearance of activated T cells from the circulation?

Mycophenolate mofetil

Cyclosporine mofetil

Corticosteroids

Daclizumab

Correct! Wrong!

[Immunology] The Transplantation Immunology Quizzes (8 tests)

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[Immunology] The Transplantation Immunology Quizzes (8 tests)

The type of allograft rejection associated with vascular and parenchymal injury with lymphocyte infiltrates is which of the following?

Antigen receptors on T lymphocytes bind HLA class II molecules with the help of which accessory molecule?

Patients at risk for graft-versus-host disease (GVHD) include each of the following, except recipients of

HLA molecules exhibit all of the following properties, except that they

Kidney allograft loss from intravascular thrombosis without cellular infiltration 5 days post-transplant raises the suspicion level about which primary rejection mechanism?

Which reagents would be used in a direct (forward) donor–recipient crossmatch test?

The indirect allorecognition pathway involves which one of the following mechanisms?

Which immunosuppressive agent selectively inhibits IL-2 receptor-mediated activation of T cells and causes clearance of activated T cells from the circulation?

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