[Immunology] The Agglutination Quizzes (12 tests)

Which of the following best describes agglutination?

A combination of soluble antigen with soluble antibody

A combination of particulate antigen with soluble antibody

A reaction that produces no visible end point

A reaction that requires instrumentation to read

Correct! Wrong!

All of the following could be used to enhance an agglutination reaction except

increasing the viscosity of the medium.

using albumin.

increasing the ionic strength of the medium.

centrifugation.

Correct! Wrong!

Agglutination of dyed bacterial cells represents which type of reaction?

Direct agglutination

Passive agglutination

Reverse passive agglutination

Agglutination inhibition

Correct! Wrong!

In which of the following circumstances would the indirect Coombs’ test be employed?

Identification of the ABO blood groups

Identification of cold-reacting antibody

Identification of an unexpected IgG antibody

Identification of hemolytic disease of the newborn

Correct! Wrong!

In an agglutination reaction, if cells are not centrifuged long enough, which of the following might occur?

False-negative result

False-positive result

No effect

Slight effect but can be ignored

Correct! Wrong!

Agglutination inhibition could best be used for which of the following types of antigens?

Large cellular antigens such as erythrocytes

Soluble haptens

Bacterial cells

Antigen attached to latex particles

Correct! Wrong!

Which of the following correctly describes reverse passive agglutination?

It is a negative test.

It can be used to detect autoantibodies.

It is used for identification of bacterial antigens.

It is used to detect sensitization of red blood cells.

Correct! Wrong!

In which of the following tests is patient antigen determined by measuring the number of nonagglutinating particles left after the reaction has taken place?

Direct agglutination

Coagglutination

PACIA

Coombs’ testing

Correct! Wrong!

Reactions involving IgG may need to be enhanced for which reason?

It is only active at 25°C.

It may be too small to produce lattice formation.

It has only one antigen-binding site.

It is not able to produce visible in vitro agglutination.

Correct! Wrong!

For which of the following tests is a lack of agglutination a positive reaction?

Hemagglutination

Passive agglutination

Reverse passive agglutination

Agglutination inhibition

Correct! Wrong!

All of the following would be considered good qualitycontrol procedures except

storing reagents properly.

standardizing temperature of reactions.

allowing the reaction to go as long as possible.

using monoclonal antibody to avoid cross-reactivity.

Correct! Wrong!

A positive direct Coombs’ test could occur under which circumstances?

Hemolytic disease of the newborn

Autoimmune hemolytic anemia

Antibodies to drugs that bind to red cells

Any of the above

Correct! Wrong!

[Immunology] The Agglutination Quizzes (12 tests)

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[Immunology] The Agglutination Quizzes (12 tests)

Which of the following best describes agglutination?

All of the following could be used to enhance an agglutination reaction except

Agglutination of dyed bacterial cells represents which type of reaction?

In which of the following circumstances would the indirect Coombs’ test be employed?

In an agglutination reaction, if cells are not centrifuged long enough, which of the following might occur?

Agglutination inhibition could best be used for which of the following types of antigens?

Which of the following correctly describes reverse passive agglutination?

In which of the following tests is patient antigen determined by measuring the number of nonagglutinating particles left after the reaction has taken place?

Reactions involving IgG may need to be enhanced for which reason?

For which of the following tests is a lack of agglutination a positive reaction?

All of the following would be considered good qualitycontrol procedures except

A positive direct Coombs’ test could occur under which circumstances?

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