Diseases of the Respiratory System – Part 2

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A 66-year-old man with chronic alcoholism has had a low grade fever and cough for several weeks. His heart sounds are normal and there are crackles in the left lower base. A CXR reveals a left lower lobe lung abscess. Which of the following is the most appropriate therapy?

Traditionally, penicillin was the treatment of choice for anaerobic lung disease. However, metronidazole plus either third-generation cephalosporin (ceftriaxone) or fluoroquinolone (levofloxacin) has a better spectrum of activity against oral anaerobes, Gram negatives, and Streptococcus pneumoniae.

Diseases of the Respiratory System – Part 2
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