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Select the one best response to each question!
Which of the following is not a function of amniotic fluid?
|1. Which of the following is not a function of amniotic fluid?
A. Allow movement of the fetus
B. Carbon dioxide and oxygen exchange
C. Protect fetus from extreme temperature changes
D. Protective cushion for the fetus
|2. What is the primary cause of the normal increase in amniotic fluid as a pregnancy progresses?
A. Fetal cell metabolism
B. Fetal swallowing
C. Fetal urine
D. Transfer of water across the placenta
|3. Which of the following is not a reason for decreased amounts of amniotic fluid?
A. Fetus fails to begin swallowing
B. Increased fetal swallowing
C. Membrane leakage
D. Urinary tract defects
|4. Why might a creatinine level be requested on an amniotic fluid?
A. Detect oligohydramnios
B. Detect polyhydramnios
C. Differentiate amniotic fluid from maternal urine
D. Evaluate lung maturity
|5. Amniotic fluid specimens are placed in ambercolored tubes prior to sending them to the laboratory to prevent the destruction of:
A. Alpha fetoprotein
C. Cells for cytogenetics
|6. How are specimens for FLM testing delivered to and stored in the laboratory?
A. Delivered on ice and refrigerated or frozen
B. Immediately centrifuged
C. Kept at room temperature
D. Delivered in a vacuum tube
|7. Why are amniotic specimens for cytogenetic analysis incubated at 37C prior to analysis?
A. To detect the presence of meconium
B. To differentiate amniotic fluid from urine
C. To prevent photo-oxidation of bilirubin to biliverdin
D. To prolong fetal cell viability and integrity
|8. Filtration of amniotic fluid is required to avoid decreased values in the test results for:
B. Fetal cells
|9. Match the following colors in amniotic fluid with their significance.
|10. A significant rise in the OD of amniotic fluid at 450 nm indicates the presence of which analyte?
|11. Plotting the amniotic fluid OD on a Liley graph represents the severity of hemolytic disease of the newborn. A value that is plotted in zone II indicates what condition of the fetus?
A. No hemolysis
B. Mildly affected fetus
C. Moderately affected fetus that requires close monitoring
D. Severely affected fetus that requires intervention
|12. The presence of a fetal neural tube disorder may be detected by:
A. Increased amniotic fluid bilirubin
B. Increased maternal serum alpha fetoprotein
C. Decreased amniotic fluid phosphatidyl glycerol
D. Decreased maternal serum acetycholinesterase
|13. True or False: An AFP MoM value greater than two times the median value is considered an indication of a neural tube disorder|
|14. When severe HDN is present, which of the following tests on the amniotic fluid would the physician not order to determine whether the fetal lungs are mature enough to withstand a premature delivery?
A. AFP levels
B. Foam stability index
C. Lecithin/sphingomyelin ratio
D. Phosphatidyl glycerol detection
|15. The foam or shake test is a screening test for which amniotic fluid substance?
C. Alpha fetoprotein
|16. True or False: Prior to 35 weeks’ gestation, the normal L/S ratio is less than 1.6.|
|17. When performing an L/S ratio by thin-layer chromatography, a mature fetal lung will show:
A. Sphingomyelin twice as concentrated as lecithin
B. No sphingomyelin
C. Lecithin twice as concentrated as sphingomyelin
D. Equal concentrations of lecithin and sphingomyelin
|18. True or False: Phosphatidyl glycerol is present with an L/S ratio of 1.1|
|19. A rapid test for FLM that does not require performance of thin-layer chromatography is:
A. AFP levels
B. Amniotic acetylcholinesterase
D. Bilirubin scan
|20. Does the failure to produce bubbles in the Foam Stability Index indicate increased or decreased lecithin?
|21. Microviscosity of amniotic fluid is measured by:
A. Thin-layer chromatography
B. Immunologic agglutination
D. Fluorescence polarization
|22. The presence of phosphatidyl glycerol in amniotic fluid fetal lung maturity tests must be confirmed when:
A. Hemolytic disease of the newborn is present
B. The mother has maternal diabetes
C. Amniotic fluid is contaminated by hemoglobin
D. Neural tube disorder is suspected
|23. Match the following principles with the appropriate FLM test.
|24. True or False: An L/S ratio of 2.0 correlates with a surfactant/albumin ratio of 39 mg/g.|
|25. A lamellar body count of 50,000 correlates with:
A. Absent phosphatidyl glycerol and TDx-FLM II ratio of 39
B. L/S ratio of 1.5 and absent phosphatidyl glycerol
C. OD at 650 nm of 1.010 and an L/S ratio of 1.1
D. OD at 650 nm of 0.150 and an L/S ratio of 2.0
|26. Which test for FLM is least affected by contamination with hemoglobin and meconium?
B. Foam Stability
C. Lamellar Bodies Count
D. TDx-FLM II