[MCQ]The Female Reproductive System, Infertility, and Contraception- Part 4

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The Female Reproductive System, Infertility, and Contraception- Part 4

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Question 1

Severe CMV disease in the newborn is characterized by all except ?

A	Chorioretinitis
B	Macrocephaly
C	Intracranial calcifications
D	Hepatitis

Question 1 Explanation:

Severe cytomegalovirus infection in newborn is characterized by petechiae, hepatosplenomegaly & jaundice. Chorioretinitis, microcephaly, intracranial calcifications, hepatitis, hemolytic anemia, and purpura may also develop

Question 2

Risk of fetal anomalies in congenital rubella is highest in ?

A	First trimester
B	Second trimester
C	Third trimester
D	Equally in all three trimesters

Question 2 Explanation:

Rubella virus is a known teratogen. First-trimester rubella carries a high risk of fetal anomalies, risk decreases later in pregnancy.

Question 3

Most primary infections of toxoplasmosis in US come from ?

A	Sex with multiple partners
B	Homosexuality
C	Eating undercooked meat
D	Use of tampoons

Question 4

Triple-drug therapy for placental/fetal toxoplasmosis includes all except ?

A	Spiramycin
B	Tetracycline
C	Pyrimethamine
D	Sulfonamide

Question 5

Which of the following does not increase the risk of mother-tochild transmission of HIV ?

A	Cesarean section
B	Preterm delivery
C	Trauma to fetal skin
D	Maternal bleeding

Question 5 Explanation:

Exposures which increase risk of mother-to-child transmission include vaginal delivery, preterm delivery, trauma to fetal skin, maternal bleeding, recent infection with high maternal viral load, low maternal CD4+ T cell count, prolonged labor, prolonged length of membrane rupture, and the presence of other genital tract infections (syphilis or herpes).

Question 6

Majority of cases of mother-to-child (vertical) transmission of HIV-1 occur during ?

A	Antepartum period
B	Intrapartum period
C	Postpartum period
D	Breast feeding

Question 6 Explanation:

Majority of mother-to-child (vertical) transmission of HIV-1 occur during intrapartum period. Mechanisms of vertical transmission is infection after rupture of membranes & direct contact of fetus with infected secretions or blood from maternal genital tract. Breast-feeding may transmit HIV to the newborn and is therefore contraindicated for HIV-infected mothers.

Question 7

Which of the following reduces the risk of vertical transmission of HIV infection ?

A	Cesarean section
B	Zidovudine therapy before & during delivery
C	Zidovudine treatment to neonate at birth
D	All of the above

Question 7 Explanation:

Zidovudine (ZDV) administered during pregnancy and labor and to the newborn reduces the risk of vertical transmission by 70%. Cesarean section is associated with additional risk reduction compared to vaginal delivery, especially in women with a viral load >1000 copies/mL. Regardless of the mode of delivery, intrapartum ZDV should be provided

Question 8

Most common causes of maternal death in United States today is ?

A	Hypertension
B	Pulmonary embolism
C	Ectopic pregnancy
D	Obstetric hemorrhage

Question 8 Explanation:

Most common causes of maternal death in US today are, in decreasing order of frequency, pulmonary embolism, obstetric hemorrhage, hypertension, sepsis, cardiovascular conditions including peripartum cardiomyopathy & ectopic pregnancy.

Question 9

Infertility is defined as the inability to conceive after how many months of unprotected sexual intercourse ?

A	3
B	6
C	9
D	12

Question 9 Explanation:

Infertility is defined as the inability to conceive after 12 months of unprotected sexual intercourse.

Question 10

Infertility can be attributed primarily to female factors in what percentage of infertile couples ?

A	28 %
B	42 %
C	58 %
D	76 %

Question 10 Explanation:

Infertility can be attributed primarily to male factors in 25%, female factors in 58%, and is unexplained in ~17% of couples.

Question 11

Secondary sexual characteristics in girls include ?

A	Thelarche
B	Pubarche
C	Adrenarche
D	All of the above

Question 12

Among the secondary sexual characteristics in girls, which of the following appears first ?

A	Development of breast buds (thelarche)
B	Development of pubic hair (pubarche)
C	Development of axillary hair (adrenarche)
D	All of the above

Question 12 Explanation:

At age 10 to 11, first secondary sexual characteristics appear in girls. They are development of the breast buds (thelarche), followed by development of pubic hair (pubarche) & later by development of axillary hair (adrenarche).

Question 13

Average time between the beginning of breast development and onset of menses i.e. menarche is ?

A	6 months
B	12 months
C	18 months
D	24 months

Question 13 Explanation:

Average time between beginning of breast development & onset of menses (menarche) is 2 years.

Question 14

Conditions that can delay menarche include all except ?

A	Active participation in sports
B	Malnutrition
C	Obesity
D	Chronic debilitating disease

Question 15

Condition that leads to early menarche is ?

A	Active participation in sports
B	Malnutrition
C	Obesity
D	Chronic debilitating disease

Question 15 Explanation:

Obese girls have earlier menarche than girls with normal body weight. Active participation in sports, malnutrition & chronic debilitating disease delay menarche.

Question 16

Which of the following determine age of menarche ?

A	Total body weight
B	Percent body fat
C	Nutrition
D	All of the above

Question 16 Explanation:

A critical combination of total body weight & percent body fat is associated with development of hypothalamic insensitivity to feedback by steroids that leads to increased secretion of gonadotropins & to menarche.

Question 17

Evidence of ovulation is provided by which of the following ?

A	Urinary ovulation predictor kits
B	Basal body temperature charts
C	Mid-luteal phase progesterone level
D	All of the above

Question 18

For confirmation of ovulation, mid-luteal phase progesterone level should be ?

A	> 0.5 ng/mL
B	> 1 ng/mL
C	> 2 ng/mL
D	> 3 ng/mL

Question 18 Explanation:

Evidence of ovulation is provided by urinary ovulation predictor kits (preovulatory gonadotropin surge), basal body temperature charts, or a mid-luteal phase progesterone rise which is usually > 3 ng/mL.

Question 19

Which of the following predicts adequate “ovarian oocyte reserve” ?

A	FSH level < 5 IU/mL on cycle day 1
B	FSH level < 5 IU/mL on cycle day 3
C	FSH level < 10 IU/mL on cycle day 1
D	FSH level < 10 IU/mL on cycle day 3

Question 19 Explanation:

Evaluation of ovarian reserve is done by measurement of FSH on day 3 of menstrual cycle or in response to clomiphene, an estrogen antagonist. An FSH level < 10 IU/mL on cycle day 3 predicts adequate ovarian oocyte reserve.

Question 20

Normal male fertility is associated with sperm count, motility and normal sperm morphology percentage of ?

A	> 48 million/mL, > 63%, > 6% respectively
B	> 48 million/mL, > 63%, > 12% respectively
C	> 48 million/mL, > 36%, > 6% respectively
D	> 48 million/mL, > 36%, > 12% respectively

Question 21

Male subfertility is associated with sperm count, motility and normal sperm morphology percentage of ?

A	< 13 million/mL, < 32%, < 9% respectively
B	< 18 million/mL, < 32%, < 9% respectively
C	< 23 million/mL, < 32%, < 9% respectively
D	< 33 million/mL, < 32%, < 9% respectively

Question 21 Explanation:

Normal male fertility is associated with sperm counts of > 48 million/mL, with a motility of > 63%, with > 12% showing normal morphology. Subfertility is seen with sperm counts of < 13 million/mL, motility of < 32%, and < 9% normal morphology

Question 22

Which of the following is true in males with “primary gonadal deficiency” ?

A	Low testosterone level
B	Elevated levels of LH
C	Elevated levels of FSH
D	All of the above

Question 22 Explanation:

Low testosterone level with raised levels of LH & FSH indicate primary gonadal deficiency.

Question 23

Which of the following is false in males with “secondary hypogonadism” ?

A	Low testosterone level
B	Low LH level
C	Low FSH level
D	Low prolactin level

Question 23 Explanation:

Decreased spermatogenesis due to hypothalamic or pituitary disease show low testosterone & decreased spermatogenesis with low LH & FSH levels.

Question 24

Congenital absence of the vas deferens can be diagnosed by ?

A	Deficiency of glucose in ejaculate
B	Deficiency of fructose in ejaculate
C	Deficiency of sucrose in ejaculate
D	Deficiency of galactose in ejaculate

Question 24 Explanation:

Congenital absence of vas deferens is diagnosed by deficiency of fructose in the ejaculate. It is often associated with an abnormality of cystic fibrosis transmembrane regulator (CFTR) gene.

Question 25

Inspissated secretions precluding normal sperm transport is seen in ?

A	Bowen syndrome
B	Hess syndrome
C	Young’s syndrome
D	Bloom syndrome

Question 25 Explanation:

Young’s syndrome, characterized by inspissated secretions, can preclude normal sperm transport.

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See all quizzes of The Female Reproductive System, Infertility, and Contraception at here:

1.Severe CMV disease in the newborn is characterized by all
except ?
A. Chorioretinitis
B. Macrocephaly
C. Intracranial calcifications
D. Hepatitis

2. Risk of fetal anomalies in congenital rubella is highest in ?
A. First trimester
B. Second trimester
C. Third trimester
D. Equally in all three trimesters

3. Most primary infections of toxoplasmosis in US come from ?
A. Sex with multiple partners
B. Homosexuality
C. Eating undercooked meat
D. Use of tampoons
4. Triple-drug therapy for placental/fetal toxoplasmosis includes all
except ?
A. Spiramycin
B. Tetracycline
C. Pyrimethamine
D. Sulfonamide
5. Which of the following does not increase the risk of mother-tochild
transmission of HIV ?
Harrison’s 17th Ed. 48
A. Cesarean section
B. Preterm delivery
C. Trauma to fetal skin
D. Maternal bleeding

6. Majority of cases of mother-to-child (vertical) transmission of
HIV-1 occur during ?
A. Antepartum period
B. Intrapartum period
C. Postpartum period
D. Breast feeding

7 Which of the following reduces the risk of vertical transmission
of HIV infection ?
A. Cesarean section
B. Zidovudine therapy before & during delivery
C. Zidovudine treatment to neonate at birth
D. All of the above

8 Most common causes of maternal death in United States today
is ?
A. Hypertension
B. Pulmonary embolism
C. Ectopic pregnancy
D. Obstetric hemorrhage

9 Infertility is defined as the inability to conceive after how many
months of unprotected sexual intercourse ?
A. 3
B. 6
C. 9
D. 12

10 Infertility can be attributed primarily to female factors in what
percentage of infertile couples ?
A. 28 %
B. 42 %
C. 58 %
D. 76 %

11 Secondary sexual characteristics in girls include ?
A. Thelarche
B. Pubarche
C. Adrenarche
D. All of the above
12 Among the secondary sexual characteristics in girls, which of the
following appears first ?
A. Development of breast buds (thelarche)
B. Development of pubic hair (pubarche)
C. Development of axillary hair (adrenarche)
D. All of the above

13 Average time between the beginning of breast development and
onset of menses i.e. menarche is ?
A. 6 months
B. 12 months
C. 18 months
D. 24 months

14 Conditions that can delay menarche include all except ?
A. Active participation in sports
B. Malnutrition
C. Obesity
D. Chronic debilitating disease
15 Condition that leads to early menarche is ?
A. Active participation in sports
B. Malnutrition
C. Obesity
D. Chronic debilitating disease

16 Which of the following determine age of menarche ?
A. Total body weight
B. Percent body fat
C. Nutrition
D. All of the above

17 Evidence of ovulation is provided by which of the following ?
A. Urinary ovulation predictor kits
B. Basal body temperature charts
C. Mid-luteal phase progesterone level
D. All of the above
18 For confirmation of ovulation, mid-luteal phase progesterone
level should be ?
A. > 0.5 ng/mL
B. > 1 ng/mL
C. > 2 ng/mL
D. > 3 ng/mL

19 Which of the following predicts adequate “ovarian oocyte
reserve” ?
A. FSH level < 5 IU/mL on cycle day 1
B. FSH level < 5 IU/mL on cycle day 3
C. FSH level < 10 IU/mL on cycle day 1
D. FSH level < 10 IU/mL on cycle day 3

20 Normal male fertility is associated with sperm count, motility and
normal sperm morphology percentage of ?
A. > 48 million/mL, > 63%, > 6% respectively
B. > 48 million/mL, > 63%, > 12% respectively
C. > 48 million/mL, > 36%, > 6% respectively
D. > 48 million/mL, > 36%, > 12% respectively
21 Male subfertility is associated with sperm count, motility and
normal sperm morphology percentage of ?
A. < 13 million/mL, < 32%, < 9% respectively
B. < 18 million/mL, < 32%, < 9% respectively
C. < 23 million/mL, < 32%, < 9% respectively
D. < 33 million/mL, < 32%, < 9% respectively

22 Which of the following is true in males with “primary gonadal
deficiency” ?
A. Low testosterone level
B. Elevated levels of LH
C. Elevated levels of FSH
D. All of the above

23 Which of the following is false in males with “secondary
hypogonadism” ?
A. Low testosterone level
B. Low LH level
C. Low FSH level
D. Low prolactin level

24 Congenital absence of the vas deferens can be diagnosed by ?
A. Deficiency of glucose in ejaculate
B. Deficiency of fructose in ejaculate
C. Deficiency of sucrose in ejaculate
D. Deficiency of galactose in ejaculate

25 Inspissated secretions precluding normal sperm transport is seen
in ?
A. Bowen syndrome
B. Hess syndrome
C. Young’s syndrome
D. Bloom syndrome

[MCQ]The Female Reproductive System, Infertility, and Contraception- Part 4

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The Female Reproductive System, Infertility, and Contraception- Part 4

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