[MCQs] Henoch-Schönlein purpura

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Henoch-Schönlein purpura

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Question 1

Which of the following is a Primary Vasculitis Syndrome ?

A	Wegener’s granulomatosis
B	Churg-Strauss syndrome
C	Henoch-Schönlein purpura
D	All of the above

Question 1 Explanation:

Primary vasculitis syndromes include Wegener’s granulomatosis, Churg-Strauss syndrome, Henoch-Schönlein purpura, Polyarteritis nodosa, Microscopic polyangiitis, Giant cell arteritis, Takayasu’s arteritis, Idiopathic cutaneous vasculitis, Essential mixed cryoglobulinemia, Behçet’s syndrome, Isolated vasculitis of CNS, Cogan’s syndrome & Kawasaki disease

Question 2

Henoch-Schönlein purpura is also referred to as ?

A	Anaphylactoid purpura
B	Purple purpura
C	Emergent purpura
D	Sympathetic purpura

Question 2 Explanation:

Henoch-Schönlein purpura is also referred to as anaphylactoid purpura.

Question 3

Henoch-Schönlein purpura lesions are most commonly distributed over ?

A	Buttocks and lower extremities
B	Neck and upper limbs
C	Chest and abdomen
D	Face

Question 3 Explanation:

In Henoch-Schönlein purpura, palpable purpura lesions are most commonly distributed over buttocks and lower extremities.

Question 4

Henoch-Schönlein purpura is often preceded by ?

A	Trauma
B	Conjunctivitis
C	Upper respiratory infection
D	Exercise

Question 4 Explanation:

Henoch-Schönlein purpura is often preceded by an upper respiratory infection (streptococcal pharyngitis) or is triggered by drug or food allergies.

Question 5

Henoch-Schönlein purpura is a ?

A	Small vessel vasculitis
B	Medium vessel vasculitis
C	Large vessel vasculitis
D	All of the above

Question 5 Explanation:

Henoch-Schönlein purpura is a small-vessel vasculitis.

Question 6

Which of the following is false about Henoch-Schönlein purpura ?

A	Mostly in age between 4 - 7 years
B	Male-to-female ratio is 1.5:1
C	Peak incidence in spring
D	None of the above

Question 6 Explanation:

Most patients of HSP are between 4 - 7 years of age. Male-to-female ratio is 1.5:1. Peak incidence in spring has been noted. All coagulation tests are normal.

Question 7

In Henoch-Schönlein purpura, the antibody class most often seen in the immune complexes is ?

A	IgA
B	IgG
C	IgM
D	IgE

Question 7 Explanation:

IgA is the antibody class most often seen in immune complexes and demonstrated in renal biopsies of HSP patients. IgA levels are elevated in ~half of patients.

Question 8

In pediatric patients, which of the following is the most common presentation in HSP ?

A	Palpable purpura
B	Gastrointestinal involvement
C	Glomerulonephritis
D	Arthritis

Question 8 Explanation:

In pediatric HSP, palpable purpura is seen in virtually all patients.

Question 9

Henoch-Schönlein purpura is best related to ?

A	Leukocytoclastic vasculitis (LCV)
B	Livedoid vasculitis
C	Necrotizing vasculitis
D	Systemic vasculitis

Question 9 Explanation:

HSP is a subtype of acute LCV. Livedoid vasculitis represents a combination of a vasculopathy plus intravascular thrombosis.

Question 10

Which of the following statements about renal involvement in Henoch-Schönlein purpura is false ?

A	Proteinuria
B	Microscopic hematuria
C	Red blood cell casts
D	Progressive glomerulonephritis frequent

Question 11

Which of the following statements about renal involvement in Henoch-Schönlein purpura is false ?

A	Usually resolves spontaneously without therapy
B	Progressive glomerulonephritis rare
C	Renal failure is the most common cause of death
D	None of the above

Question 11 Explanation:

Renal involvement occurs in 10 - 50% of HSP patients. Mild glomerulonephritis, proteinuria, microscopic hematuria, with RBC casts occurs in the majority. it resolves spontaneously without therapy. Rarely, a progressive glomerulonephritis will develop

Question 12

Which of the following statements about gastrointestinal involvement in Henoch-Schönlein purpura is false ?

A	Colicky abdominal pain
B	Blood and mucus per rectum
C	Bowel intussusception
D	None of the above

Question 13

In Henoch-Schönlein purpura, mesangial immune deposits consists of ?

A	IgA
B	IgG
C	C3
D	All of the above

Question 14

In Henoch-Schönlein purpura, immune deposits may be found in ?

A	Mesangial and paramesangial areas
B	Peripheral glomerular capillary wall
C	Small arterioles
D	All of the above

Question 14 Explanation:

D. Arthritis In pediatric HSP, palpable purpura is seen in virtually all patients. 991 Henoch-Schönlein purpura is best related to ? Harrison’s 18th Ed. 2797 A. Leukocytoclastic vasculitis (LCV) B. Livedoid vasculitis C. Necrotizing vasculitis D. Systemic vasculitis HSP is a subtype of acute LCV. Livedoid vasculitis represents a combination of a vasculopathy plus intravascular thrombosis. 992 Which of the following statements about renal involvement in Henoch-Schönlein purpura is false ? Harrison’s 18th Ed. 2797 A. Proteinuria B. Microscopic hematuria C. Red blood cell casts D. Progressive glomerulonephritis frequent 993 Which of the following statements about renal involvement in Henoch-Schönlein purpura is false ? Harrison’s 18th Ed. 2797 A. Usually resolves spontaneously without therapy B. Progressive glomerulonephritis rare C. Renal failure is the most common cause of death D. None of the above Renal involvement occurs in 10 - 50% of HSP patients. Mild glomerulonephritis, proteinuria, microscopic hematuria, with RBC casts occurs in the majority. it resolves spontaneously without therapy. Rarely, a progressive glomerulonephritis will develop. 994 Which of the following statements about gastrointestinal involvement in Henoch-Schönlein purpura is false ? Harrison’s 18th Ed. 2797 A. Colicky abdominal pain B. Blood and mucus per rectum C. Bowel intussusception D. None of the above 995 In Henoch-Schönlein purpura, mesangial immune deposits consists of ? Harrison’s 18th Ed. 2797 A. IgA B. IgG C. C3 D. All of the above 996 In Henoch-Schönlein purpura, immune deposits may be found in ? Harrison’s 18th Ed. 2797 HSP patients have an acute inflammatory reaction with IgA and complement components in capillaries, mesangial tissues, and small arterioles, leading to increased vascular permeability and localized hemorrhage

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II. Preview all questions below:

1. Which of the following is a Primary Vasculitis Syndrome ?
A. Wegener’s granulomatosis
B. Churg-Strauss syndrome
C. Henoch-Schönlein purpura
D. All of the above

2. Henoch-Schönlein purpura is also referred to as ?
A. Anaphylactoid purpura
B. Purple purpura
C. Emergent purpura
D. Sympathetic purpura

3. Henoch-Schönlein purpura lesions are most commonly distributed over ?
A. Buttocks and lower extremities
B. Neck and upper limbs
C. Chest and abdomen
D. Face

4. Henoch-Schönlein purpura is often preceded by ?
A. Trauma
B. Conjunctivitis
C. Upper respiratory infection
D. Exercise

5. Henoch-Schönlein purpura is a ?
A. Small vessel vasculitis
B. Medium vessel vasculitis
C. Large vessel vasculitis
D. All of the above

6. Which of the following is false about Henoch-Schönlein purpura ?
A. Mostly in age between 4 – 7 years

B. Male-to-female ratio is 1.5:1
C. Peak incidence in spring
D. None of the above

7. In Henoch-Schönlein purpura, the antibody class most often seen in the immune complexes is ?
A. IgA
B. IgG
C. IgM
D. IgE

8. In pediatric patients, which of the following is the most common presentation in HSP ?
A. Palpable purpura
B. Gastrointestinal involvement
C. Glomerulonephritis
D. Arthritis

9. Henoch-Schönlein purpura is best related to ?
A. Leukocytoclastic vasculitis (LCV)
B. Livedoid vasculitis
C. Necrotizing vasculitis
D. Systemic vasculitis

10. Which of the following statements about renal involvement in Henoch-Schönlein purpura is false ?
A. Proteinuria
B. Microscopic hematuria
C. Red blood cell casts
D. Progressive glomerulonephritis frequent

11. Which of the following statements about renal involvement in Henoch-Schönlein purpura is false ?
A. Usually resolves spontaneously without therapy
B. Progressive glomerulonephritis rare
C. Renal failure is the most common cause of death
D. None of the above

12. Which of the following statements about gastrointestinal involvement in Henoch-Schönlein purpura is false ?
A. Colicky abdominal pain

B. Blood and mucus per rectum
C. Bowel intussusception
D. None of the above

13. In Henoch-Schönlein purpura, mesangial immune deposits consists of ?
A. IgA
B. IgG
C. C3
D. All of the above

14. In Henoch-Schönlein purpura, immune deposits may be found in ?
A. Mesangial and paramesangial areas
B. Peripheral glomerular capillary wall
C. Small arterioles
D. All of the above

Henoch-Schönlein Henoch-Schönlein purpura

[MCQs] Henoch-Schönlein purpura

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Henoch-Schönlein purpura

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