I. Start the exam by click the “Start” button
NUCLEIC ACIDS- Part 12
See all quizzes of NUCLEIC ACIDS- Part 12 here:
1 Anticodons are present on
(A) Coding strand of DNA
(B) mRNA
(C) tRNA
(D) rRNA
2. Codons are present on
(A) Non-coding strand of DNA
(B) hnRNA
(C) tRNA
(D) None of these
3. Nonsense codons are present on
(A) mRNA (B) tRNA
(C) rRNA (D) None of these
4. Genetic code is said to be degenerate because
(A) It can undergo mutations
(B) A large proportion of DNA is non-coding
(C) One codon can code for more than one amino
acids
(D) More than one codons can code for the same
amino acids
5. All the following statements about genetic
code are correct except
(A) It is degenerate (B) It is unambigous
(C) It is nearly universal(D) It is overlapping
6. All of the following statements about
nonsense codons are true except
(A) They do not code for amino acids
(B) They act as chain termination signals
(C) They are identical in nuclear and
mitochondrial DNA
(D) They have no complementary anticodons
7. A polycistronic mRNA can be seen in
(A) Prokaryotes (B) Eukaryotes
(C) Mitochondria (D) All of these
8. Non-coding sequence are present in the
genes of
(A) Bacteria (B) Viruses
(C) Eukaryotes (D) All of these
9. Non-coding sequences in a gene are known
as
(A) Cistrons (B) Nonsense codons
(C) Introns (D) Exons
10. Splice sites are present in
(A) Prokaryotic mRNA (B) Eukaryotic mRNA
(C) Eukaryotic hnRNA (D) All of these
11. The common features of introns include
all the following except
(A) The base sequence begins with GU
(B) The base sequence ends with AG
(C) The terminal AG sequence is preceded by a
purine rich tract of ten nucleotides
(D) An adenosine residue in branch site participates
in splicing
12. A splice some contains all the following
except
(A) hnRNA (B) snRNAs
(C) Some proteins (D) Ribosome
13. Self-splicing can occur in
(A) Some precursors of rRNA
(B) Some precursors of tRNA
(C) hnRNA
(D) None of these
14. Pribnow box is present in
(A) Prokaryotic promoters
(B) Eukaryotic promoters
(C) Both (A) and (B)
(D) None of these
15. Hogness box is present in
(A) Prokaryotic promoters
NUCLEIC ACIDS 257
(B) Eukaryotic promoters
(C) Both (A) and (B)
(D) None of these
16. CAAT box is present in
(A) Prokaryotic promoters 10 bp upstream of
transcription start site
(B) Prokaryotic promoters 35 bp upstream of
transcription start site
(C) Eukaryotic promoters 25 bp upstream of
transcription start site
(D) Eukaryotic promoters 70–80 bp upstream of
transcription start site
17. Eukaryotic promoters contain
(A) TATA box 25bp upstream of transcription start
site
(B) CAAT box 70-80 bp upstream of transcription
start site
(C) Both (A) and (B)
(D) None of these
18. All the following statements about tRNA
are correct except
(A) A given tRNA can be charged with only one
particular amino acid
(B) The amino acid is recognized by the
anticodon of tRNA
(C) The amino acid is attached to end of tRNA
(D) The anticodon of tRNA finds the complementary
codon on mRNA
19. All the following statements about
charging of tRNA are correct except
(A) It is catalysed by amino acyl tRNA synthetase
(B) ATP is converted into ADP and Pi in this
reaction
(C) The enzyme recognizes the tRNA and the
amino acid
(D) There is a separate enzyme for each tRNA
20. All the following statements about
recognition of a codon on mRNA by an
anticodon on tRNA are correct except
(A) The recognition of the third base of the codon
is not very precise
(B) Imprecise recognition of the third base results
in wobble
(C) Wobble is partly responsible for the
degeneracy of the genetic code
(D) Wobble results in incorporation of incorrect
amino acids in the protein
21. The first amino acyl tRNA which initiates
translation in eukaryotes is
(A) Mehtionyl tRNA
(B) Formylmethionyl tRNA
(C) Tyrosinyl tRNA
(D) Alanyl tRNA
22. The first amino acyl tRNA which initiates
translation in prokaryotes is
(A) Mehtionyl tRNA
(B) Formylmethionyl tRNA
(C) Tyrosinyl tRNA
(D) Alanyl tRNA
23. In eukaryotes, the 40 S pre-initiation
complex contains all the following
initiation factors except
(A) eIF-1A (B) eIF-2
(C) eIF-3 (D) eIF-4
24. Eukaryotic initiation factors 4A, 4B and
4F bind to
(A) 40 S ribosomal subunit
(B) 60 S ribosomal subunit
(C) mRNA
(D) Amino acyl tRNA
25. The codon which serves as translation
start signal is
(A) AUG (B) UAG
(C) UGA (D) UAA
26. The first amino acyl tRNA approaches
40 S ribosomal subunit in association with
(A) eIF-1A and GTP (B) eIF-2 and GTP
(C) eIF-2C and GTP (D) eIF-3 and GTP
27. eIF-1A and eIF-3 are required
(A) For binding of amino acyl tRNA to 40 S
ribosomal subunit
(B) For binding of mRNA to 40 S ribosomal
subunit
(C) For binding of 60 S subunit to 40 S subunit
(D) To prevent binding of 60 S subunit to 40 S
subunit
28. eIF-4 A possesses
(A) ATPase activity (B) GTPase activity
(C) Helicase activity (D) None of these
29. eIF-4 B
(A) Binds to 3’ chain initiation codon on mRNA
(B) Binds to 3’ end of mRNA
(C) Binds to 5’ end of mRNA
(D) Unwinds mRNA near its 5’ end
30. Peptidyl transferase activity is present in
(A) 40 S ribosomal subunit
(B) 60 S ribosomal subunit
(C) eEF-2
(D) Amino acyl tRNA
