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HORMONE METABOLISM- Part 8
See all quizzes of HORMONE METABOLISM- Part 8 here:
1 All the following may occur in myxoedema
except
(A) Cold intolerance (B) Low BMR
(C) Tachycardia (D) Dry and coarse skin
2. Mental retardation can occur in
(A) Cretinism
(B) Juvenile myxoedema
(C) Myxoedema
(D) Juvenile thyrotoxicosis
3. Parathyroid hormone (PTH) is synthesised
in
(A) Chief cells of parathyroid glands
(B) Oxyphil cells of parathyroid glands
(C) Para follicular cells of thyroid glands
(D) Follicular cells of thyroid gland
4. The number of amino acid residues in PTH:
(A) 51 (B) 84
(C) 90 (D) 115
5. Amino acid residues which are essential
for the biological activity of PTH are
(A) N-terminal 34 amino acids
(B) N-terminal 50 amino acids
(C) C-terminal 34 amino acids
(D) C-terminal 50 amino acids
6. Half-life of PTH is
(A) A few seconds (B) A few minutes
(C) A few hours (D) A few days
7. The second messenger for PTH is
(A) Cyclic AMP (B) Cyclic GMP
(C) Diacylglycerol (D) Inositol triphosphate
8. PTH causes all of the following except
(A) Increased intestinal absorption of calcium
(B) Increased intestinal absorption of phosphate
(C) Increased tubular reabsorption of calcium
(D) Increased tubular reabsorption of phosphate
9. Secretion of PTH is regulated by
(A) Hypothalamus
(B) Anterior pituitary
(C) Feedback effect of plasma PTH
(D) Feedback effect of plasma calcium
10. A high concentration of PTH in blood
causes
(A) Increase in plasma calcium and inorganic
phosphorous
(B) Decrease in plasma calcium and inorganic
phosphorous
(C) Increase in plasma calcium and decrease in
plasma inorganic phosphorous
(D) Decrease in plasma calcium and increase in
plasma inorganic phosphorous
11. Tetany can occur
(A) In primary hyperparathyroidism
(B) In secondary hyperparathyroidism
(C) In idiopathic hypoparathyroidism
(D) After accidental removal of parathyroid glands
12. Crystallisation of insulin occurs in the
presence of
(A) Chromium (B) Copper
(C) Zinc (D) Calcium
223. Daily secretion of insulin is about δ–
(A) 10–20 mg (B) 40–50 mg
(C) 10–20 units (D) 40–50 units
14. Insulin receptors are decreased in number
in
(A) Obesity (B) Starvation
(C) Hyperinsulinism (D) Kwashiorkor
15. Insulin binding sites are present on the
(A) α-subunits of insulin receptor
(B) β-subunits of insulin receptor
(C) γ-subunits of insulin receptor
(D) α-and β−subunits of insulin receptor
16. α-Subunits of insulin receptor are present
(A) Outside the cell membrane
(B) In the cell membrane
(C) Across the cell membrane
(D) In the cytosol
17. β-Subunits of insulin receptor are present
(A) Outside the cell membrane
(B) In the cell membrane
(C) Across the cell membrane
(D) In the cytosol
18. In the insulin receptor, tyrosine kinase
domain is present in
(A) α-Subunits (B) β-Subunits
(C) γ-Subunits (D) δ-Subunits
19. Binding of insulin to its receptor activates
(A) Adenylate cyclase (B) Guanylate cyclase
(C) Phospholipase C (D) Tyrosine kinase
20. Insulin receptor is made up of
(A) One α-and one β-subunit
(B) Two α-and two β-subunit
(C) Two, α two β-and two γ-subunit
(D) One α, one β-one γ-and one δ-subunit
21. Insulin is required for the active uptake
of glucose by most of the cells except
(A) Muscle cells (B) Renal tubular cells
(C) Adipocytes (D) Liver cells
22. Insulin decreases
(A) Glycogenesis
(B) Glyolysis
(C) Gluconeogenesis
(D) Tubular reabsorption of glucose
23. Insulin increases
(A) Glycogenesis (B) Gluconeogenesis
(C) Lipolysis (D) Blood glucose
24. Insulin increases
(A) Protein synthesis (B) Fatty acid synthesis
(C) Glycogen synthesis (D) All of these
25. Insulin decreases the synthesis of
(A) Hexokinase (B) Glucokinase
(C) PEP carboxykinase (D) Glycogen synthetase
26. Diabetes mellitus can occur due to all of
the following except
(A) Deficient insulin secretion
(B) Tumour of β−cells
(C) Decrease in number of insulin receptors
(D) Formation of insulin antibodies
27. Hypoglycaemic coma can occur
(A) In untreated diabetes mellitus
(B) In starvation
(C) After overdose of oral hypoglycaemic drugs
(D) After overdose of insulin
28. Second messenger for glucagons is
(A) Cyclic AMP (B) Diacylglycerol
(C) Cyclic GMP (D) Inositol triphosphate
29. Number of amino acid residues in
glucagons is
(A) 29 (B) 34
(C) 51 (D) 84
20. Glucagon secretion increases
(A) After a carbohydrate-rich meal
(B) After a fat-rich meal
(C) When blood glucose is high
(D) When blood glucose is low
