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HORMONE METABOLISM- Part 6
See all quizzes of HORMONE METABOLISM- Part 6 here:
1 The nucleotide binding site of G-proteins
is present on their
(A) α-Subunit (B) β-Subunit α- and β-
(C) γ-Subunit (D) δ-Subunit
2. Adenylate cyclase is activated by
(A) GDP-bearing α-Subunit of G-protein
(B) GTP-bearing α-Subunit of G-protein
(C) GDP-bearing γ-Subunit of G-protein
(D) GTP-bearing γ-Subunit of G-protein
3. Tyrosine kinase activity is present in
(A) α-Adrenergic receptors
(B) β-Adrenergic receptors
(C) Cholinergic receptors
(D) Insulin receptors
4. Insulin receptor is a
(A) Monomer (B) Dimer
(C) Trimer (D) Tetramer
5. Tyrosine kinase activity is present in
(A) Acetylcholine receptor
(B) PDGF receptor
(C) ADH receptor
(D) All of these
6. Protein kinase C is activated by
(A) Cyclic AMP (B) Cyclic GMP
(C) Diacyl glycerol (D) Inositol triphosphate
7. Melatonin is synthesised in
(A) Hypothalamus
(B) Posterior pituitary gland
(C) Pineal gland
(D) Melanocytes
8. Melatonin is synthesised from
(A) Phenylalanine (B) Tyrosine
(C) Tryptophan (D) None of these
9. Melanocyte stimulating hormone is
secreted by
(A) Pineal gland
(B) Anterior lobe of pituitary gland
(C) Posterior lobe of pituitary gland
(D) Intermediate lobe of pituitary gland
10. MSH causes
(A) Dispersal of melanin granules in melanocytes
(B) Increase in melanin concentration in melanocytes
(C) Decerease in melanin concentration in melanocytes
(D) Increase in number of melanocytes
11. Secretion of MSH is regulated by
(A) Feedback mechanism
(B) Melatonin
(C) Hypothalamic hormones
(D) ACTH
12. A hormone synthesised in the hypothalamus
is
(A) Melatonin
(B) Melanocyte stimulating hormone
(C) Vasopressin
(D) Prolactin
13. Posterior pituitary gland secretes
(A) Catecholamines
(B) Oxytocin
(C) Follicle stimulating hormone
(D) Serotonin
14. A nonapeptide among the following is
(A) Antidiuretic hormone
(B) Insulin
(C) ACTH
(D) Thyrotropin releasing hormone
15. Diabetes insipidus is caused by deficient
secretion of
(A) Insulin (B) Glucagon
(C) Vasopressin (D) Oxytocin
16. Peripheral vasoconstriction is caused by
high concentrations of
(A) Antidiuretic hormone
(B) Melatonin
(C) Glucagon
(D) Oxytocin
17. Somatotropin is secreted by
(A) Hypothalamus (B) Anterior pituitary
(C) Posterior pituitary (D) Thyroid gland
18. Secretion of Insulin-like Growth Factor-I
is promoted by
(A) Insulin (B) Glucagon
(C) Growth hormone (D) Somatomedin C
19. Growth hormone increases
(A) Protein synthesis (B) Lipogenesis
(C) Glycogenolysis (D) All of these
20. Secretion of growth hormone is inhibited
by
(A) Somatomedin C (B) Somatostatin
(C) Feedback inhibition(D) All of these
21. Secretion of somatotrophin is promoted
by
(A) Somatomedin C
(B) Somatostatin
(C) Growth hormone releasing hormone
(D) Hypoglycaemia
22. Human growth hormone has
(A) One polypeptide chain and one intra-chain
disulphide bond
(B) One polypeptide chain and two intra-chain
disulphide bond
(C) Two polypeptide chains joined by one
disulphide bond
(D) Two polypeptide chains joined by two
disulphide bond
23. Number of amino acid residues in human
growth hormone is
(A) 51 (B) 84
(C) 191 (D) 198
24. Number of amino acid residues in
prolactin is
(A) 51 (B) 84
(C) 191 (D) 198
25. Secretion of prolactin is regulated by
(A) Feedback inhibition
(B) Prolactin releasing hormone
(C) Prolactin release inhibiting hormone
(D) All of these
26. Precursor of ACTH is
(A) Cholesterol (B) Pregnenolone
(C) Corticotropin (D) Pro-opiomelanocortin
27. All of the following can be formed from
pro-opiomelanocortin except
(A) α-and β-MSH (B) β-and γ-Lipotropins
(C) α-and β-Endorphins(D) FSH
28. All the following statements about proopiomelanocortin
are true except
(A) It is made up of 285 amino acids
(B) It is synthesised in pars intermedia and
anterior lobe of pituitary gland
(C) It is the precursor of ACTH and melatonin
(D) It is the precursor of corticotropin like
intermediate lobe peptide and endorphins
29. All the following statements about ACTH
are true except
(A) It is a tropic hormone
(B) Its target cells are located in adrenal cortex
(C) Its receptors are located in the cell membrane
(D) Its second messenger is inositol triphosphate
30. Regulation of ACTH secretion occurs
through
(A) Corticotropin releasing hormone (CRH) and
corticotropin release inhibiting hormone (CRIH)
of hypothalamus
(B) Feedback inhibition by cortisol
(C) CRH and feedback inhibition by cortisol
(D) CRIH and feedback inhibition by cortisol
