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PROTEINS AND PROTEIN METABOLISM- Part 9
See all quizzes of PROTEINS AND PROTEIN METABOLISM- Part 9 here:
1 Immunoglobulins are classified on the
basis of
(A) Type of light chains
(B) Type of heavy chains
(C) Types of light and heavy chains
(D) Molecular weight
2. The molecular weight of light chains is
(A) 10,000–15,000 (B) 20,000–25,000
(C) 25,000–50,000 (D) 50,000–75,000
3. The molecular weight of heavy chains is
(A) 20,000–25,000 (B) 25,000–50,000
(C) 50,000–70,000 (D) 70,000–1,00,000
4. Secretory component is present in
(A) IgA (B) IgG
(C) IgM (D) All of these
5. The variable region of light chains is the
(A) N-terminal quarter (B) N-terminal half
(C) C-terminal quarter (D) C-terminal half
PROTEINS AND PROTEIN METABOLISM 41
6. The variable region of light chain is the
(A) N-terminal quarter
(B) N-terminal half
(C) C-terminal quarter
(D) C-terminal half
7. The variable region of light chains has
(A) One hypervariable region
(B) Two hypervariable regions
(C) Three hypervariable regions
(D) Four hypervariable regions
8. The variable region of heavy chains has
(A) One hypervariable region
(B) Two hypervariable regions
(C) Three hypervariable regions
(D) Four hypervariable regions
9. The most abundant immunoglobulin in
plasma is
(A) IgA (B) IgG
(C) IgM (D) IgD
10. The largest immunoglobulin is
(A) IgA (B) IgG
(C) IgM (D) IgD
11. The plasma concentration of IgA is
(A) 1–5 mg/dl (B) 40–200 mg/dl
(C) 60–500 mg/dl (D) 700–1,500 mg/dl
12. An immunoglobulin found in exocrine
secretions is
(A) IgA (B) IgG
(C) IgM (D) IgE
13. Allergic reactions are mediated by
(A) IgA (B) IgG
(C) IgD (D) IgE
14. An immunoglobulin which can cross the
placental barrier is
(A) IgA (B) IgM
(C) IgD (D) None of these
15. IgM possesses
(A) Two light chains and two heavy chains
(B) Four light chains and four heavy chains
(C) Six light chains and six heavy chains
(D) Ten light chains and ten heavy chains
16. The immunoglobulin having the longest
half-life is
(A) IgA (B) IgG
(C) IgM (D) IgE
17. The half-life of IgG is
(A) 2–3 days (B) 5–6 days
(C) 8–10 days (D) 20–25 days
18. Recognition of antigen is the function of
(A) Variable region of light chains
(B) Variable regions of light and heavy chains
(C) Constant region of heavy chains
(D) Constant regions of light and heavy chains
19. The effector function of antibody is
performed by
(A) Variable region of light chains
(B) Constant region of heavy chains
(C) Variable regions of light and heavy chains
(D) Constant regions of light and heavy chains
20. Complement system can be activated by
binding of antigen to
(A) IgA (B) IgD
(C) IgE (D) IgM
21. C1 component of classical complement
pathway is made up of
(A) Complements 1q and 1r
(B) Complements 1q and 1s
(C) Complements 1r and 1s
(D) Complements 1q, 1r and 1s
22. The components of complement system
are activated by
(A) Microsomal hydroxylation
(B) Phosphorylation
(C) Glycosylation
(D) Proteloysis
23. The component system forms a membrane
attack complex made up of
(A) Complements 1q, 1r and 1s
(B) Complements 1, 2, 3 and 4
(C) Complements 5b, 6, 7 and 8
(D) Factors B and D
24. Factors B and D are required in
(A) The classical pathway of complement fixation
(B) The alternate complement pathway
(C) Both (A) and (B)
(D) None of these
25. The alternate complement pathway
doesn’t involve
(A) Antigen-antibody complex
(B) Complement 3
(C) Factors B and D
(D) Membrane attack unit
26. Antibody diversity arises from
(A) Gene amplification
(B) Gene re-arrangement
(C) Alternative splicing
(D) All of these
27. A light chain gene is constructed from the
following segments:
(A) Variable and constant segments
(B) Variable, joining and constant segments
(C) Variable, diversity and constant segments
(D) Variable, joining, diversity and constant
segments
28. In metabolic point of view, amino acids
are classified as
(A) Glycogenic
(B) Ketogenic
(C) Glycogenic or Ketogenic
(D) All of these
29. Diversity segments are present in
(A) Light chain genes
(B) Heavy chain genes
(C) Light and heavy chain genes
(D) None of these
30. Constant segments of heavy chains are
of
(A) Five types (B) Six types
(C) Seven types (D) Eight types
