[MCQ] Myocarditis- Part 2

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Myocarditis- Part 2

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Question 1

Which of the following drugs should be avoided while treating cocaine-induced cardiotoxicity ?

A	Nitrates
B	Calcium channel blockers
C	Beta-adrenergic blockers
D	Benzodiazepines

Question 1 Explanation:

Nitrates, calcium channel blockers (to reduce coronary spasm) & benzodiazepines are used to treat cocaine-induced cardiotoxicities. Beta-adrenergic blockers should be avoided.

Question 2

Which of the following is a cardioprotective agent when doxorubicin (Adriamycin) is given to a patient ?

A	Erythropoietin
B	Dexrazoxone
C	Amiodarone
D	Cyclophosphamide

Question 2 Explanation:

Iron chelator dexrazoxone is cardioprotective and reduces risk of doxorubicin (Adriamycin) cardiotoxicity. Recovery of cardiac function occurs with aggressive use of ACE inhibitors

Question 3

Which of the following drug causes dilated cardiomyopathy ?

A	Trastuzumab (Herceptin)
B	Ifosfamide
C	Cyclophosphamide
D	Cyclophosphamide

Question 4

Which of the following chemotherapeutic agents can cause recurrent coronary spasm ?

A	Cyclophosphamide
B	Ifosfamide
C	Cisplatin
D	All of the above

Question 4 Explanation:

5-Fluorouracil, cisplatin, and some other alkylating agents can cause recurrent coronary spasm.

Question 5

Which of the following drugs can cause cardiotoxicity with chronic use ?

A	Hydroxychloroquine
B	Chloroquine
C	Emetine
D	All of the above

Question 6

Heart failure with “preserved” ejection fraction is best applied to ?

A	Hyperthyroidism
B	Hypothyroidism
C	Obesity
D	Diabetes

Question 6 Explanation:

Diabetes is a typical factor, along with hypertension, advanced age, and female gender, in heart failure with “preserved” ejection fraction.

Question 7

Which of the following conditions is associated with a high risk of death in patients with viral myocarditis ?

A	Pulmonary hypertension
B	Pericardial friction rub
C	Arrhythmias
D	Heart failure

Question 7 Explanation:

Patients with viral myocarditis & pulmonary hypertension are at a particularly high risk of death

Question 8

Deficiency of which of the following plays a pathogenetic role in peripartum cardiomyopathy ?

A	Gold
B	Zinc
C	Copper
D	Selenium

Question 8 Explanation:

Pathogenetic factors in peripartum cardiomyopathy include low socioeconomic status, high parity, prolonged lactation, excessive dietary salt intake & selenium deficiency.

Question 9

“Wet beri-beri heart disease” is characterized by all except ?

A	Third heart sound
B	Cold extremities
C	Reduced ECG voltage
D	Prolongation of QT interval

Question 9 Explanation:

“Wet beri-beri heart disease” is characterized by high cardiac output failure state & is associated with tachycardia, wide pulse pressure, S3, & warm extremities. ECG shows reduced voltage, diffuse T-wave abnormalities & prolongation of QT interval.

Question 10

While treating “wet beri-beri heart disease” with thiamine, which of the following drugs should be accompanied ?

A	Digoxin
B	Theophyllin
C	Quinidine
D	Diuretics

Question 10 Explanation:

Response to thiamine in “wet beri-beri heart disease” is dramatic & must be accompanied by diuretics

Question 11

Which of the following diseases is associated with selenium deficiency ?

A	Keshan Disease
B	Kashin-Beck Disease
C	Myxedematous Endemic Cretinism
D	All of the above

Question 11 Explanation:

Specific diseases associated with selenium deficiency are Keshan Disease, Kashin-Beck Disease (Big Bone disease) and Myxedematous Endemic Cretinism.

Question 12

Which of the following is best absorbed & utilized form of selenium ?

A	Selenothiamine
B	Selenoarginine
C	Selenoleucine
D	Selenomethionine

Question 13

Recommended Dietary Allowances (RDA) for selenium for adults is ?

A	50 µg/day
B	500 µg/day
C	5000 µg/day
D	50000 µg/day

Question 13 Explanation:

Recommended Dietary Allowances (RDA) for selenium for adults is 50-200 µg/day

Question 14

Clinical syndrome of Hemochromatosis includes ?

A	Cirrhosis
B	Diabetes
C	Hypogonadism
D	All of the above

Question 14 Explanation:

The clinical syndrome of Hemochromatosis includes cirrhosis, diabetes & hypogonadism.

Question 15

Which of the following is false about Hemochromatosis ?

A	May be due to iron overload as in hemolytic anemia
B	Iron deposited in perinuclear area of cardiomyocytes
C	Transferrin saturation > 60 % for men
D	None of the above

Question 16

In right ventricular dysplasia, there is progressive replacement of right ventricular wall with ?

A	Elastic tissue
B	Collagen tissue
C	Adipose tissue
D	Mucopolysaccharides

Question 16 Explanation:

RV dysplasia is a familial cardiomyopathy marked by progressive replacement of right ventricular wall with adipose tissue. Ventricular arrhythmias are common & sudden death is a constant threat.

Question 17

Which of the following is mostly affected in Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia (ARVC/D)

A	Nuclear membrane
B	Endoplasmic reticulum
C	Mitochondria
D	Desmosomes

Question 17 Explanation:

ARVC/D is an autosomal dominant disorder caused by multiple mutations of several genes encoding proteins that constitute desmosomes, structures that maintain normal contacts between cells leading to detachment of myocytes with consequent myocyte apoptosis and fibrofatty replacement.

Question 18

Which of the following best relates to genetic defect in the desmosomal protein ?

A	Strabismus
B	Gait disturbance
C	Woolly hair
D	Cyanosis

Question 18 Explanation:

Genetic defects in proteins of the desmosomal complex disrupt myocyte junctions & adhesions, leading to replacement of myocardium by deposits of fat. This same protein also affects hair & skin, leading in to a distinct syndrome of “woolly hair” and thickened palms and soles

Question 19

Drooping eyelids is a feature of ?

A	Hemochromatosis
B	Duchenne’s and Becker’s dystrophy
C	Mitochondrial myopathies
D	Hypothyroidism

Question 19 Explanation:

Mitochondrial myopathies show the characteristic “ragged red fiber” appearance. Some patients with mitochondrial myopathy have characteristic drooping eyelids

Question 20

Cardinal clinical feature of left ventricular noncompaction is ?

A	Ventricular arrhythmias
B	Embolic events
C	Heart failure
D	All of the above

Question 20 Explanation:

The three cardinal clinical features of left ventricular noncompaction are ventricular arrhythmias, embolic events, and heart failure.

Question 21

Which of the following is false about Left Ventricular Noncompaction ?

A	Congenital cardiomyopathy
B	Abnormal embryogenesis
C	Multiple deep trabeculations into myocardium
D	None of the above

Question 21 Explanation:

Left ventricular noncompaction (LVNC) is a congenital cardiomyopathy that may present at any age with symptoms of CHF, thromboembolism or ventricular arrhythmias due to arrest of normal embryogenesis, with persistence of multiple deep trabeculations into myocardium communicating with ventricular cavity, 2 layered structure of endomyocardium leading to LV contractile dysfunction. It is diagnosed echocardiographically.

Question 22

Left ventricular noncompaction is best related to ?

A	Restanin
B	Tafazzin
C	Gibazin
D	Frufin

Question 22 Explanation:

Diagnostic criteria of left ventricular noncompaction includes presence of multiple trabeculations in left ventricle distal to papillary muscles, creating a “spongy” appearance of apex. It is associated with multiple genetic variants in sarcomeric and other proteins such as tafazzin.

Question 23

What does “tako tsubo” in Japanese language mean ?

A	Japanese baloon
B	Japanese parachute
C	Japanese pot for fishing octopus
D	Japanese fishing net

Question 23 Explanation:

“Tako-tsubo” in Japanese language refers to a Japanese pot for fishing for octopus.

Question 24

Which of the following is false about Tako-Tsubo (stress) cardiomyopathy ?

A	Also known as apical ballooning syndrome
B	Severe chest discomfort preceded by stressful emotional or physical event
C	Occurs mostly in women >50 years
D	None of the above

Question 24 Explanation:

Also known as apical ballooning syndrome, Tako-Tsubo (stress) cardiomyopathy is characterized by abrupt & severe chest discomfort preceded by a stressful emotional or physical event. It occurs mostly in women >50 years.

Question 25

Which of the following is false about Tako-Tsubo (Stress) Cardiomyopathy ?

A	ST elevations &/or T-wave inversions in chest leads
B	Normal coronary angiography
C	ECG & Echo CG changes revert in 3-7 days
D	None of the above

Question 25 Explanation:

ECG in Tako-Tsubo (stress) cardiomyopathy shows ST-segment elevations and/or deep T-wave inversions in chest leads. Coronary angiography shows no obstruction in epicardial arteries. Severe akinesia of distal portion of left ventricle with EF reduction occurs. Troponins are mildly elevated. Changes are reversible in 3 - 7 days without consequences.

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See all quizzes of the Myocarditis at here:

Myocarditis- Part 1 | Myocarditis- Part 2

1.Which of the following drugs should be avoided while treating cocaine-induced cardiotoxicity ?
A. Nitrates
B. Calcium channel blockers
C. Beta-adrenergic blockers
D. Benzodiazepines

2. Which of the following is a cardioprotective agent when doxorubicin (Adriamycin) is given to a patient ?
A. Erythropoietin
B. Dexrazoxone
C. Amiodarone
D. Cyclophosphamide

3. Which of the following drug causes dilated cardiomyopathy ?
A. Trastuzumab (Herceptin)
B. Ifosfamide
C. Cyclophosphamide
D. All of the above
4. Which of the following chemotherapeutic agents can cause recurrent coronary spasm ?
A. Cyclophosphamide
B. Ifosfamide
C. Cisplatin
D. All of the above
5. 5-Fluorouracil, cisplatin, and some other alkylating agents can cause recurrent coronary spasm. 1001 Which of the following drugs can cause cardiotoxicity with chronic use ?
A. Hydroxychloroquine
B. Chloroquine
C. Emetine
D. All of the above
6. Heart failure with “preserved” ejection fraction is best applied to ?
A. Hyperthyroidism
B. Hypothyroidism
C. Obesity
D. Diabetes

7. Which of the following conditions is associated with a high risk of death in patients with viral myocarditis ?
A. Pulmonary hypertension
B. Pericardial friction rub
C. Arrhythmias
D. Heart failure

8. Deficiency of which of the following plays a pathogenetic role in peripartum cardiomyopathy ?

A. Gold
B. Zinc
C. Copper
D. Selenium

9. “Wet beri-beri heart disease” is characterized by all except ?
A. Third heart sound
B. Cold extremities
C. Reduced ECG voltage
D. Prolongation of QT interval

10. While treating “wet beri-beri heart disease” with thiamine, which of the following drugs should be accompanied ?
A. Digoxin
B. Theophyllin
C. Quinidine
D. Diuretics

11. Which of the following diseases is associated with selenium deficiency ?
A. Keshan Disease
B. Kashin-Beck Disease
C. Myxedematous Endemic Cretinism
D. All of the above

12. Which of the following is best absorbed & utilized form of selenium ?
A. Selenothiamine
B. Selenoarginine
C. Selenoleucine
D. Selenomethionine

13. Recommended Dietary Allowances (RDA) for selenium for adults is ?
A. 50 µg/day
B. 500 µg/day
C. 5000 µg/day
D. 50000 µg/day

14. Clinical syndrome of Hemochromatosis includes ?
A. Cirrhosis

B. Diabetes
C. Hypogonadism
D. All of the above

15. Which of the following is false about Hemochromatosis ?

A. May be due to iron overload as in hemolytic anemia
B. Iron deposited in perinuclear area of cardiomyocytes
C. Transferrin saturation > 60 % for men
D. None of the above
16. In right ventricular dysplasia, there is progressive replacement of right ventricular wall with ?
A. Elastic tissue
B. Collagen tissue
C. Adipose tissue
D. Mucopolysaccharides

17. Which of the following is mostly affected in Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia (ARVC/D)
A. Nuclear membrane
B. Endoplasmic reticulum
C. Mitochondria
D. Desmosomes

18. Which of the following best relates to genetic defect in the desmosomal protein ?
A. Strabismus
B. Gait disturbance
C. Woolly hair
D. Cyanosis

19. Drooping eyelids is a feature of ?
A. Hemochromatosis
B. Duchenne’s and Becker’s dystrophy
C. Mitochondrial myopathies
D. Hypothyroidism

20, Cardinal clinical feature of left ventricular noncompaction is ?
A. Ventricular arrhythmias
B. Embolic events

C. Heart failure
D. All of the above

21. Which of the following is false about Left Ventricular Noncompaction ?
A. Congenital cardiomyopathy
B. Abnormal embryogenesis
C. Multiple deep trabeculations into myocardium
D. None of the above

22. Left ventricular noncompaction is best related to ?
A. Restanin
B. Tafazzin
C. Gibazin
D. Frufin

23. What does “tako tsubo” in Japanese language mean ?
A. Japanese baloon
B. Japanese parachute
C. Japanese pot for fishing octopus
D. Japanese fishing net

24. Which of the following is false about Tako-Tsubo (stress) cardiomyopathy ?
A. Also known as apical ballooning syndrome
B. Severe chest discomfort preceded by stressful emotional or physical event
C. Occurs mostly in women >50 years
D. None of the above

25. Which of the following is false about Tako-Tsubo (Stress) Cardiomyopathy ?
A. ST elevations &/or T-wave inversions in chest leads
B. Normal coronary angiography
C. ECG & Echo CG changes revert in 3-7 days
D. None of the above

Myocarditis

[MCQ] Myocarditis- Part 2

I. Start the exam by click the “Start” button

Myocarditis- Part 2

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