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Mental Disorders- Part 3
See all quizzes of Mental Disorders- Part 3 here:
1 “Dysthymia” is the term used for ?
A. Persistent, residual depressive symptoms
B. Generalized weakness
C. Absence of sweating
D. Difficulty in swallowing
2 As regards risk of problems in depressed patients, which of the
following statements is true ?
A. Suicide
B. Heart disease
C. Stroke
D. All of the above
3 Which of the following about depression is false ?
A. Elevated cortisol levels
B. Higher levels of N-acetyl aspartate
C. Deficiencies of serotonin, norepinephrine, dopamine & GABA
D. Overactivity of acetylcholine, corticotropin-releasing factor,
and substance P
4 Disordered neurocircuitry in depression is observed in which of
the following structures ?
A. Anterior and posterior cingulate cortex
B. Ventral, medial, and dorsolateral prefrontal cortex
C. Insula
D. All of the above
5 Disordered neurocircuitry in depression is observed in which of
the following structures ?
A. Ventral striatum
B. Hippocampus
C. Medial thalamus
D. All of the above
6 Tricyclic antidepressants have greater efficacy than SSRIs in ?
A. Severe major depressive disorder
B. Depression with melancholic features
C. Depression in which physical symptoms or pain are prominent
D. All of the above
7 Which of the following drugs has no direct action on the serotonin
system ?
A. Bupropion
B. Venlafaxine
C. Duloxetine
D. Milnacipran
8 Monoamine oxidase (MAO) is the enzyme involved in ?
A. Norepinephrine breakdown
B. Epinephrine breakdown
C. Dopamine breakdown
D. All of the above
9 Mirtazapine blocks ?
A. Alpha2-adrenergic autoreceptors
B. Serotonin 5-HT2A and 5-HT3 receptors
C. Histamine H1 receptors
D. All of the above
10 Which of the following are classified as mood stabilizers ?
A, Lithium
B. Lamotrigine
C. Divalproex
D. All of the above
11 ECT can be a first-line treatment for patients who have ?
A. Severe major depressive disorder with psychotic features
B. Psychomotor retardation
C. Medication resistance
D. All of the above
12 Depressive symptoms can be caused by which of the following
group of drugs ?
A. Antihypertensive drugs
B. Anticholesterolemic drugs
C. Antiarrhythmic drugs
D. All of the above
13 Iatrogenic depression can be caused by which of the following
group of drugs ?
A. Glucocorticoids
B. Antimicrobials
C. Systemic analgesics
D. All of the above
14 Which amino acid is the precursor of serotonin ?
A. Tryptophan
B. Leucine
C. Isoleucine
D. Arginine
15 Which Tricyclic antidepressant carries the greatest risk in
overdose ?
A. Desipramine
B. Imipramine
C. Nortriptyline
D. Amitriptyline
16 Akathisia refers to ?
A. Phobias for high pitched sounds
B. Inner sense of restlessness and anxiety
C. Obsession for cleanliness
D. Transient blindness
17 SSRI induced sexual dysfunction can be ameliorated by ?
A. Amantadine
B. Bethanechol
C. Buspirone
D. All of the above
18 Which of the following about Mirtazapine is false ?
A. Tetracyclic antidepressant
B. Increases noradrenergic & serotonergic neurotransmission
C. Strongly antihistaminic
D. Does not inhibit cytochrome P450 enzymes
19 Which of the following SSRIs does not inhibit one or more
cytochrome P450 enzymes ?
A. Sertraline
B. Citalopram
C. Fluoxetine
D. Paroxetine
20 Mania in its pure form is associated with ?
A. Increased psychomotor activity
B. Impulsivity and impairment in judgment
C. Decreased need for sleep
D. All of the above
21 Drug for treatment of bipolar disorders include ?
A. Lithium carbonate
B. Sodium valproate
C. Olanzapine
D. All of the above
22 Which of the following about lithium therapy is false ?
A. Side effects include polyuria & weight gain
B. Lithium exerts an antithyroid effect
C. No prophylactic effect in prevention of recurrent mania
D. Excreted mainly by kidneys
23 Akinetic mutism can be caused by ?
A. Damage of the medial thalamic nuclei
B. Damage of the frontal lobes
C. Hydrocephalus
D. All of the above
24 Mild form of akinetic mutism is called ?
A. Agnosia
B. Abulia
C. Akathesia
D. None of the above
25 Hypomobile and mute syndrome associated with a major psychosis
is ?
A. Catatonia
B. Abulia
C. Agnosia
D. Akathesia
26 Beclouded dementia refers to ?
A. Acute medical problem, or a poorly tolerated medication
supervenes in a mildly demented patient
B. Transient confusion & drowsiness with febrile infection
C. Awake but unresponsive state
D. Awake but cannot produce speech
27 MASA syndrome includes all except ?
A. Mental retardation
B. Aphasia
C. Syncope
D. Adducted thumbs
