[MCQ] Mental Disorders- Part 1

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Mental Disorders- Part 1

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Congratulations - you have completed Mental Disorders- Part 1. You scored %%SCORE%% out of %%TOTAL%%. Your performance has been rated as %%RATING%%

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Question 1

General medical condition leading to mental disorders is denoted by which of the following in the multiaxial system of classification ?

A	Axis I
B	Axis II
C	Axis III
D	Axis IV

Question 2

In DSM-IV-PC, axis III disorders refer to ?

A	Presence or absence of a major mental disorder
B	Any underlying personality disorder
C	General medical condition
D	Psychosocial and environmental problems

Question 2 Explanation:

The revised fourth edition for use by primary care physicians of the Diagnostic and Statistical Manual (DSM-IV-PC) provides the current multiaxial system of classification. Presence or absence of a major mental disorder (axis I), any underlying personality disorder (axis II), general medical condition (axis III), psychosocial and environmental problems (axis IV), and overall rating of general psychosocial functioning (axis V).

Question 3

Subjective sense of unease best relates to ?

A	Anxiety
B	Panic attack
C	Obsessive-compulsive disorder
D	All of the above

Question 3 Explanation:

Anxiety disorders are the most prevalent psychiatric illnesses. Anxiety is defined as a subjective sense of unease, dread, or foreboding.

Question 4

Agoraphobia commonly accompanies ?

A	Anxiety disorder
B	Panic disorder
C	Obsessive-compulsive disorder
D	All of the above

Question 4 Explanation:

Agoraphobia occurs commonly in patients with panic disorder. It is an acquired irrational fear of being in places where one might feel trapped or unable to escape.

Question 5

Which of the following can evoke an attack of panic disorder ?

A	Intravenous infusion of sodium lactate
B	Carbon dioxide inhalation
C	Cholecystokinin tetrapeptide (CCK-4)
D	All of the above

Question 5 Explanation:

IV sodium lactate, alpha2-adrenergic antagonist yohimbine, cholecystokinin tetrapeptide (CCK-4), and carbon dioxide inhalation evoke a panic attack in panic disorder patients by activating a pathway involving noradrenergic neurons in locus coeruleus and serotonergic neurons in dorsal raphe. Agents that block serotonin reuptake can prevent attacks.

Question 6

Which of the following is a serotonin-norepinephrine reuptake inhibitor (SNRI) ?

A	Fluoxetine
B	Venlafaxine
C	Paroxetine
D	Sertraline

Question 7

Which of the following tricyclic antidepressants (TCA) is best tolerated, especially by elderly ?

A	Amitriptyline
B	Nortriptyline
C	Imipramine
D	Doxepin

Question 8

MAOIs should not be used concomitantly with ?

A	Selective serotonin reuptake inhibitors (SSRIs)
B	Serotonin-norepinephrine reuptake inhibitor (SNRI)
C	Tricyclic antidepressants (TCA)
D	All of the above

Question 8 Explanation:

MAOIs should not be used concomitantly with SSRIs, because of the risk of serotonin syndrome, or with TCAs, because of possible hyperadrenergic effects

Question 9

Which of the following is a mixed norepinephrine/serotonin reuptake inhibitors and receptor blocker ?

A	Venlafaxine
B	Duloxetine
C	Mirtazapine
D	All of the above

Question 9 Explanation:

Venlafaxine, Desvenlafaxine, Duloxetine, Mirtazapine are mixed norepinephrine/serotonin reuptake inhibitors and receptor blockers.

Question 10

Which of the following is a monoamine oxidase inhibitor (MAOI) ?

A	Amoxapine
B	Bupropion
C	Phenelzine
D	Trazodone

Question 10 Explanation:

Phenelzine, Tranylcypromine, Isocarboxazid, and Transdermal selegiline are MAOI.

Question 11

Extrapyramidal symptoms can appear with the use of ?

A	Amoxapine
B	Bupropion
C	Phenelzine
D	Trazodone

Question 12

Which of the following anxiolytic drugs has no active metabolite ?

A	Oxazepam
B	Temazepam
C	Clonazepam
D	All of the above

Question 12 Explanation:

Oxazepam, Temazepam, Clonazepam, Lorazepam, and Triazolam have no active metabolites. Diazepam, Alprazolam, Chlordiazepoxide, and Buspirone have active metabolites.

Question 13

Which of the following is to be avoided when monoamine oxidase inhibitors (MAOIs) are used ?

A	Tobacco
B	Coffee
C	Wine
D	Whisky

Question 13 Explanation:

Patients taking monoamine oxidase inhibitors (MAOIs) need to maintain a low-tyramine diet i.e. avoidance of cheese and wine.

Question 14

Benzodiazepines should not be prescribed for more than how many weeks to avoid risk of abuse and dependence ?

A	1 - 2 weeks
B	2 - 3 weeks
C	3 - 4 weeks
D	4 - 6 weeks

Question 14 Explanation:

Benzodiazepines should not be prescribed for >4 - 6 weeks because of the development of tolerance and the risk of abuse and dependence

Question 15

Which of the following is not a long-acting benzodiazepine

A	Diazepam
B	Alprazolam
C	Flurazepam
D	Clonazepam

Question 15 Explanation:

Longer-acting benzodiazepines are diazepam, chlordiazepoxide, flurazepam, and clonazepam. Shorter-acting benzodiazepines are alprazolam and oxazepam. It is more difficult to taper patients off shorter-acting benzodiazepines.

Question 16

Which of the following is a nonbenzodiazepine anxiolytic agent ?

A	Diazepam
B	Buspirone
C	Flurazepam
D	Clonazepam

Question 16 Explanation:

Buspirone is a nonbenzodiazepine anxiolytic agent. It is nonsedating, does not produce tolerance or dependence, does not interact with benzodiazepine receptors or alcohol, and has no abuse or disinhibition potential. But, requires several weeks to take effect and thrice-daily dosing.

Question 17

Which of the following anticonvulsants with GABAergic properties is beneficial in anxiety-related syndromes ?

A	Gabapentin
B	Pregabalin
C	Divalproex
D	All of the above

Question 17 Explanation:

Anticonvulsants with GABAergic properties like gabapentin, oxcarbazepine, tiagabine, pregabalin, and divalproex are beneficial in anxiety-related syndromes.

Question 18

Obsessive-compulsive disorder (OCD), obsession pertains to ?

A	Thoughts
B	Actions
C	Behaviour
D	All of the above

Question 18 Explanation:

Obsessive-compulsive disorder (OCD) is characterized by obsessive thoughts and compulsive behaviors that impair everyday functioning.

Question 19

Obsessive-compulsive disorder (OCD) is related to which of the following clinical conditions ?

A	Wilson’s Disease
B	Myoclonus
C	Tourette’s Syndrome
D	Parkinson’s disease

Question 19 Explanation:

Family studies show an aggregation of OCD with Tourette’s disorder. Both are more common in males and in first-born children

Question 20

Which of the following part of the brain is responsible for acquisition and maintenance of habit and skill learning ?

A	Hippocampus
B	Amygdala
C	Caudate nucleus
D	Mamillary bodies

Question 20 Explanation:

Anatomical localization of obsessive-compulsive behavior is to orbital frontal cortex, caudate nucleus, & globus pallidus. Caudate nucleus is involved in acquisition & maintenance of habit & skill learning.

Question 21

Which of the following is useful in the treatment of obsessivecompulsive disorder (OCD) ?

A	Clomipramine
B	Fluoxetine
C	Fluvoxamine
D	All of the above

Question 21 Explanation:

Clomipramine, fluoxetine, fluvoxamine, and sertraline are useful in the treatment of OCD. In treatment-resistant cases, augmentation with buspirone, neuroleptic or benzodiazepine is beneficial and in severe cases deep brain stimulation is effective.

Question 22

Which of the following can produce hyperglycemia and carbohydrate craving ?

A	MAOI
B	TCAs
C	SSRIs
D	All of the above

Question 22 Explanation:

MAOIs can induce hypoglycemia and weight gain, while TCAs can produce hyperglycemia and carbohydrate craving. SSRIs, like MAOIs, may reduce fasting plasma glucose

Question 23

In patients with depression, mood is worse in ?

A	Morning
B	Afternoon
C	Evening
D	Night

Question 23 Explanation:

Major depression is defined as depressed mood on a daily basis for a minimum duration of 2 weeks. Patients with depression often notice a diurnal variation in mood, worse in morning hours

Question 24

Presence of which of the following significantly increases nearterm suicidal risk in depressed patients ?

A	Anxiety
B	Agitation
C	Panic
D	All of the above

Question 24 Explanation:

Presence of anxiety, panic, or agitation significantly increases near-term suicidal risk in depressed patients.

Question 25

Neuroendocrine abnormality that reflect neurovegetative signs & symptoms of depression is ?

A	Increased cortisol & CRH secretion
B	Increase in adrenal size
C	Decreased inhibitory response of glucocorticoids to dexamethasone
D	All of the above

Question 25 Explanation:

Neuroendocrine abnormalities that reflect the neurovegetative signs & symptoms of depression include increased cortisol and corticotropin-releasing hormone (CRH) secretion, increase in adrenal size, decreased inhibitory response of glucocorticoids to dexamethasone and blunted response of thyroid-stimulating hormone (TSH) level to infusion of thyroid-releasing hormone (TRH). Antidepressant treatment normalises these abnormalities. Major depression is also associated with an upregulation of proinflammatory cytokines, which also normalizes with antidepressant treatment.

Question 26

Sleep abnormality in patients with major depression is ?

A	Decrease in REM sleep
B	Increase in REM density
C	Decrease in stage IV delta slow-wave sleep
D	All of the above

Question 26 Explanation:

Patients with major depression show a decrease in rapid eye movement (REM) sleep onset (REM latency), an increase in REM density, and, a decrease in stage IV delta slow-wave sleep.

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See all quizzes of Mental Disorders- Part 1 here:

1 General medical condition leading to mental disorders is
denoted by which of the following in the multiaxial system of
classification ?
A. Axis I
B. Axis II
C. Axis III
D. Axis IV
2 In DSM-IV-PC, axis III disorders refer to ?
A. Presence or absence of a major mental disorder
B. Any underlying personality disorder
C. General medical condition
D. Psychosocial and environmental problems

3 Subjective sense of unease best relates to ?
A. Anxiety
B. Panic attack
C. Obsessive-compulsive disorder
D. All of the above

4 Agoraphobia commonly accompanies ?
A. Anxiety disorder
B. Panic disorder
C. Obsessive-compulsive disorder
D. All of the above

5 Which of the following can evoke an attack of panic disorder ?
A. Intravenous infusion of sodium lactate
B. Carbon dioxide inhalation
C. Cholecystokinin tetrapeptide (CCK-4)
D. All of the above

6 Which of the following is a serotonin-norepinephrine reuptake
inhibitor (SNRI) ?
A. Fluoxetine
B. Venlafaxine
C. Paroxetine
D. Sertraline

7 Which of the following tricyclic antidepressants (TCA) is best
tolerated, especially by elderly ?
A. Amitriptyline
B. Nortriptyline
C. Imipramine
D. Doxepin
8 MAOIs should not be used concomitantly with ?
A. Selective serotonin reuptake inhibitors (SSRIs)
B. Serotonin-norepinephrine reuptake inhibitor (SNRI)
C. Tricyclic antidepressants (TCA)
D. All of the above

9 Which of the following is a mixed norepinephrine/serotonin
reuptake inhibitors and receptor blocker ?
A. Venlafaxine
B. Duloxetine
C. Mirtazapine
D. All of the above

10 Which of the following is a monoamine oxidase inhibitor (MAOI) ?
A. Amoxapine
B. Bupropion
C. Phenelzine
D. Trazodone

11 Extrapyramidal symptoms can appear with the use of ?
A. Amoxapine
B. Bupropion
C. Phenelzine
D. Trazodone
12 Which of the following anxiolytic drugs has no active metabolite ?
A. Oxazepam
B. Temazepam
C. Clonazepam
D. All of the above

13 Which of the following is to be avoided when monoamine oxidase
inhibitors (MAOIs) are used ?
A. Tobacco
B. Coffee
C. Wine
D. Whisky

14 Benzodiazepines should not be prescribed for more than how
many weeks to avoid risk of abuse and dependence ?
A. 1 – 2 weeks
B. 2 – 3 weeks
C. 3 – 4 weeks
D. 4 – 6 weeks

15 Which of the following is not a long-acting benzodiazepine ?
A. Diazepam
B. Alprazolam
C. Flurazepam
D. Clonazepam

16 Which of the following is a nonbenzodiazepine anxiolytic agent ?
A. Diazepam
B. Buspirone
C. Flurazepam
D. Clonazepam

17 Which of the following anticonvulsants with GABAergic properties
is beneficial in anxiety-related syndromes ?
A. Gabapentin
B. Pregabalin
C. Divalproex
D. All of the above

18 Obsessive-compulsive disorder (OCD), obsession pertains to ?
A. Thoughts
B. Actions
C. Behaviour
D. All of the above

19 Obsessive-compulsive disorder (OCD) is related to which of the
following clinical conditions ?
A. Wilson’s Disease
B. Myoclonus
C. Tourette’s Syndrome
D. Parkinson’s disease

20 Which of the following part of the brain is responsible for
acquisition and maintenance of habit and skill learning ?
A. Hippocampus
B. Amygdala
C. Caudate nucleus
D. Mamillary bodies

21 Which of the following is useful in the treatment of obsessivecompulsive
disorder (OCD) ?
A. Clomipramine
B. Fluoxetine
C. Fluvoxamine
D. All of the above

22 Which of the following can produce hyperglycemia and
carbohydrate craving ?
A. MAOI
B. TCAs
C. SSRIs
D. All of the above

23 In patients with depression, mood is worse in ?
A. Morning
B. Afternoon
C. Evening
D. Night

24 Presence of which of the following significantly increases nearterm
suicidal risk in depressed patients ?
A. Anxiety
B. Agitation
C. Panic
D. All of the above

25 Neuroendocrine abnormality that reflect neurovegetative signs &
symptoms of depression is ?
A. Increased cortisol & CRH secretion
B. Increase in adrenal size
C. Decreased inhibitory response of glucocorticoids to
dexamethasone
D. All of the above

26 Sleep abnormality in patients with major depression is ?
A. Decrease in REM sleep
B. Increase in REM density
C. Decrease in stage IV delta slow-wave sleep
D. All of the above

Mental Disorders- Part 1

[MCQ] Mental Disorders- Part 1

I. Start the exam by click the “Start” button

Mental Disorders- Part 1

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