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Malaria- Part 2
See all quizzes of Malaria- Part 2 here:
1 In Africa, the most effective mosquito vector of malaria is ?
A. Anopheles stephensi
B. Anopheles gambiae
C. Anopheles costalis
D. Anopheles sinensis
2 The entomologic inoculation rate is ?
A. Number of sporozoite (+) mosquito bites/year
B. Number of sporozoite (+) mosquito bites/person/year
C. Number of sporozoite (+) mosquito bites/person
D. Number of sporozoite (+) mosquito bites
3 Malaria pigment is also called ?
A. Hemoverdin
B. Hemosiderin
C. Hemophyte
D. Hemozoin
4 Cytoadherence in P. falciparum infection is mainly due to ?
A. PfEMP1
B. PfEMP2
C. PfEMP3
D. PfEMP4
5 In P. falciparum infections, “knobs” appear on RBC’s surface
how many hours after the cell’s invasion ?
A. 5 – 10 hours
B. 12 – 15 hours
C. 24 – 30 hours
D. 36 – 48 hours
6 In Plasmodium falciparum infection, which of the following
microbial ligand interacts with host receptor Glycophorin A ?
A. Erythrocyte-binding protein 165 (EBA-165)
B. Erythrocyte-binding protein 175 (EBA-175)
C. Erythrocyte-binding protein 185 (EBA-185)
D. Erythrocyte-binding protein 195 (EBA-195)
7 Vascular receptor that mediate cytoadherence in P. falciparum
infection include all except ?
A. Intercellular adhesion molecule 1 (ICAM-1)
B. Chondroitin sulfate B
C. CD36
D. PfEMP1
8 Which of the following processes is central to the pathogenesis of
falciparum malaria ?
A. Cytoadherence
B. Rosetting
C. Agglutination
D. All of the above
9 Process of P. falciparum infected RBCs adhering to uninfected
RBCs is called ?
A. Agglutination
B. Cytoadherence
C. Rosette
D. All of the above
10 Process of P. falciparum infected RBCs adhering to other
parasitized RBCs is called ?
A. Agglutination
B. Cytoadherence
C. Rosette
D. All of the above
11 Premunition refers to ?
A. Infection without illness
B. Malarial prodrome
C. Malarial sequele
D. Repeated malarial infection
12 Which of the following has the least duration of intrahepatic phase ?
A. P. falciparum
B. P. vivax
C. P. malariae
D. P. ovale
13 Which of the following releases least number of merozoites per
infected hepatocyte ?
A. P. falciparum
B. P. vivax
C. P. malariae
D. P. ovale
14 Which of the following has the longest duration of erythrocytic
cycle ?
A. P. falciparum
B. P. vivax
C. P. malariae
D. P. ovale
15 Pigment colour of which of the following is “black” ?
A. P. falciparum
B. P. vivax
C. P. malariae
D. P. ovale
16 Which of the following is not a “benign” human malaria ?
A. P. vivax
B. P. ovale
C. P. malariae
D. P. falciparum
17 Which of the following has preference for older RBC’s ?
A. P. falciparum
B. P. vivax
C. P. malariae
D. P. ovale
18 The level of parasitemia in P. vivax, P. ovale, and P. malariae
seldom exceeds ?1
A. 2 %
B. 5 %
C. 8 %
D. 10 %
19 Total proportion of infected RBC’s of >2% corresponds to ?
A. 106 parasites
B. 108 parasites
C. 1010 parasites
D. 1012 parasites
20 Which of the following genetic disorders confers protection against
death from falciparum malaria ?
A. Sickle cell disease
B. Ovalocytosis
C. G6PD deficiency
D. All of the above
21 In malarial immune individuals, serum levels of which of the
following increase ?
A. IgM
B. IgG
C. IgA
D. All of the above
22 The fever never becomes regular in ?
A. P. vivax
B. P. ovale
C. P. malariae
D. P. falciparum
23 Death rate in adults with coma due to falciparum malaria is ?
A. ~ 5 %
B. ~ 10 %
C. ~ 15 %
D. ~ 20 %
24 Which of the following about cerebral malaria is false ?
A. Diffuse symmetric encephalopathy
B. Focal neurologic signs are unusual
C. Pout reflex is uncommon
D. Abdominal and cremasteric reflexes are absent
25 Hypoglycemia in malaria is due to ?
A. Failure of hepatic gluconeogenesis
B. Increased consumption of glucose by host & parasite
C. Use of quinine & quinidine
D. All of the above
26 Poor prognostic clinical features in severe falciparum malaria are
all except ?
A. Hyperventilation
B. Hyperthermia
C. Anuria
D. Seizures
