[MCQ] Malaria-Dengue fever- Part 2

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1 Purpuric eruptions may occur in which of the following
illnesses ?
A. Rocky Mountain spotted fever
B. Endocarditis
C. Dengue fever
D. All of the above

2 Over the past decade, incidence of dengue has increased
particularly in which region ?
A. Caribbean
B. Latin America
C. Southeast Asia
D. All of the above

3 In febrile returned travelers, dengue was acquired most often
from ?
A. Southern Asia
B. Southeast Asia
C. Latin America
D. Africa

4 Viral hemorrhagic fevers are caused by which group of viruses ?
A. Arenaviridae
B. Bunyaviridae
C. Flaviviridae
D. All of the above

5 Which of the following virus infection is also transmitted from
person to person ?
A. Lassa fever
B. Yellow fever
C. Hantavirus hemorrhagic fever with renal syndrome
D. Dengue fever
6 Which of the following virus infection is also transmitted from
person to person ?
A. Lassa fever
B. Ebola virus infections
C. Marburg virus infections
D. All of the above

7Vectors for most viral fevers are found in rural areas except ?
A. Lassa fever
B. Ebola virus infections
C. Hantavirus hemorrhagic fever with renal syndrome
D. Dengue fever

8 In dengue hemorrhagic fever, mortality rates are ?
A. 2 – 10 %
B. 10 – 20 %
C. 30 – 40 %
D. 60 – 70 %

9 Which of the following can be transmitted by blood transfusion ?
A. Babesiosis
B. Chagas disease
C. Dengue
D. All of the above

10 Severe muscle pain is the hallmark of which of the following
infections ?
A. Influenza
B. Cysticercosis
C. Coxsackievirus B
D. Dengue

11 Positive tourniquet test for capillary fragility is ?
A. 5 or more petechiae appear in a 1 sq. inch
B. 10 or more petechiae appear in a 1 sq. inch
C. 15 or more petechiae appear in a 1 sq. inch
D. 20 or more petechiae appear in a 1 sq. inch

12 Tourniquet test is performed by inflating a blood pressure cuff on
the upper arm to ?
A. Above systolic BP for 5 minutes
B. Below diastolic BP for 5 minutes
C. Between systolic and diastolic BP for 5 minutes
D. All of the above

13Which of the following statements about dengue hemorrhagic
fever (DHF) is false ?
A. Capillary leakage, accompanied by hemorrhagic manifestations
B. Plasma leakage develops about a week later after defervescence
C. Sudden change from fever to hypothermia may be the first
clinical warning sign
D. Often associated with a marked decrease in platelet count

14 For the diagnosis of DHF, which of the following is false ?
A. Hemorrhagic manifestations
B. Platelet count of < 100,000 per cubic millimeter
C. Objective evidence of plasma leakage
D. Hemorrhagic manifestations without capillary leakage also
constitute dengue hemorrhagic fever

15 Which of the following statements about dengue shock syndrome
(DSS) is false ?
A. Rapid, weak pulse with a narrowing pulse pressure
B. Profound hypotension
C. Duration of shock is short & mortality rate is ~40 %
D. Dengue shock syndrome in travelers is common

16 A confirmed diagnosis of dengue fever is established by ?
A. Culture of the virus
B. Polymerase-chain-reaction (PCR) tests
C. Serologic assays
D. All of the above

17 Which of the following statements about IgM capture ELISA used
for diagnosis of dengue fever is false ?
A. Negative early in the course of disease
B. Rheumatoid factor may lead to false positive assay
C. Other flavivirus infections never test positive
D. IgM antibodies are detectable for 3 to 6 months, whereas IgG
antibodies remain detectable for life

18 Which of the following is false about primary infection of dengue
virus ?
A. Increase in dengue-specific IgM and IgG antibodies
B. IgM antibodies appear 4 to 5 days after onset of fever
C. IgG antibodies appear 7 to 10 days after onset of fever
D. None of the above

19 Criterion for secondary infection of dengue virus is ?
A. Presence of high titers of IgG early in disease course
B. Absence of high titers of IgG early in disease course
C. Presence of high titers of IgM early in disease course
D. Absence of high titers of IgM early in disease course

20 Which of the following rules out the diagnosis of dengue ?
A. If symptoms begin > 2 weeks after leaving endemic area
B. Fever that persists for > 10 days
C. Leucocytosis
D. All of the above

21 Which of the following is a laboratory diagnostic option in a
patient with suspected dengue infection ?
A. Detection of viral nucleic acid
B. Detection of nonstructural protein 1 (NS1)
C. IgM seroconversion
D. All of the above

22 Which of the following therapeutic agents have a role in
management of dengue ?
A. Corticosteroids
B. Carbazochrome
C. Antiviral agents
D. None of the above
23 Drugs that have shown some antiviral activity against dengue in
vitro is ?
A. Ribavirin
B. Interferon alfa
C. 6-azauridine
D. All of the above

24 Which of the following antiviral drug has been evaluated in patients
with confirmed dengue virus infection ?
A. Docosanolf
B. Balapiravir
C. Zanamivir
D. Foscarnet

25 Which of the following is best related to A. aegypti mosquito
control ?
A. Ehrlichia
B. Anaplasma
C. Wolbachia
D. Neorickettsia.

26 Which of the following statements about management of dengue
fever is false ?
A. Aspirin and NSAID’s are avoided
B. Intramuscular injections are avoided
C. Rise in PCV of 20 % indicates considerable plasma loss
D. None of the above
270 Incubation period of Chikungunya virus is ?
Harrison’s 17th Ed. 1234
A. 1 to 2 days
B. 2 to 3 days
C. 3 to 4 days