[MCQ] Inflammatory bowel disease- Part 4

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Inflammatory bowel disease- Part 4

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Congratulations - you have completed Inflammatory bowel disease- Part 4. You scored %%SCORE%% out of %%TOTAL%%. Your performance has been rated as %%RATING%%

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Question 1

Which of the following can cause proctitis ?

A	Gonorrhea
B	Chlamydia
C	Syphilis
D	All of the above

Question 1 Explanation:

Gonorrhea, Chlamydia, and syphilis can cause proctitis

Question 2

Which of the following can cause watery diarrhea ?

A	Salmonella
B	Shigella
C	C. difficile
D	All of the above

Question 2 Explanation:

Apart from above three, the main symptom in Collagenous colitis is chronic watery diarrhea.

Question 3

Parasitic infections that mimic IBD include all except ?

A	Necator americanus
B	Necator americanus
C	Strongyloides stercoralis
D	Strongyloides stercoralis

Question 3 Explanation:

Parasitic infections that may mimic IBD include hookworm (Necator americanus), whipworm (Trichuris trichiura), Strongyloides stercoralis, Isospora belli and Entamoeba histolytica

Question 4

Which of the following IBD patients are at higher risk for developing extraintestinal manifestations ?

A	IBD with Selective IgA deficiency
B	IBD with granulomas
C	Perianal Crohn’s disease
D	IBD with Turner’s syndrome

Question 5

Patients with inflammatory bowel disease are at risk for ?

A	Primary sclerosing cholangitis
B	Primary sclerosing cholangitis
C	Psoriasis
D	All of the above

Question 5 Explanation:

Patients with IBD are at risk for primary sclerosing cholangitis, ankylosing spondylitis, and psoriasis.

Question 6

Which of the following is false about collagenous colitis ?

A	Increased subepithelial collagen deposition
B	Male to female ratio is 9:1
C	Most patients present in 6th or 7th decades
D	Main symptom is chronic watery diarrhea

Question 6 Explanation:

Female to male ratio is 9:1

Question 7

Which of the following is false about Erythema nodosum (EN) in IBD ?

A	Correlate with bowel activity
B	Develop after onset of bowel symptoms
C	Concomitant active peripheral arthritis
D	None of the above

Question 7 Explanation:

EN occurs in ~15% of CD and 10% of UC patients. Attacks correlate with bowel activity, develop after onset of bowel symptoms, and frequently have concomitant active peripheral arthritis.

Question 8

Which of the following is false about Erythema nodosum (EN) in IBD ?

A	Correlate with bowel activity
B	Develop after onset of bowel symptoms
C	Concomitant active peripheral arthritis
D	None of the above

Question 8 Explanation:

EN occurs in ~15% of CD and 10% of UC patients. Attacks correlate with bowel activity, develop after onset of bowel symptoms, and frequently have concomitant active peripheral arthritis.

Question 9

Which of the following is false about Erythema nodosum ?

A	Erythematous tender nodules
B	1-5 cm in diameter
C	Found on anterior surface of lower legs and arms
D	None of the above

Question 9 Explanation:

Lesions of EN are hot, red, tender nodules measuring 1–5 cm in diameter and found on anterior surface of lower legs, ankles, calves, thighs and arms

Question 10

Which of the following is false about Pyoderma gangrenosum (PG) in IBD ?

A	May occur years before onset of bowel symptoms
B	Independent of the bowel disease
C	Respond poorly to colectomy
D	None of the above

Question 11

Which of the following is false about Pyoderma gangrenosum (PG) ?

A	Found on dorsal surface of feet and legs
B	Usually begins as a macule
C	May be single or multiple
D	Difficult to treat

Question 11 Explanation:

PG usually begins as a pustule and then spreads concentrically to rapidly undermine healthy skin.

Question 12

Dermatologic manifestations of IBD include all except ?

A	Erythema nodosum (EN)
B	Pyoderma gangrenosum (PG)
C	Pyoderma vegetans
D	Erythema marginatum

Question 13

Dermatologic manifestations of IBD include all except ?

A	Pyostomatitis vegetans
B	Alopecia
C	Perianal skin tags
D	Psoriasis

Question 14

Which of the following skin lesions is most frequent in CD ?

A	Erythema nodosum (EN)
B	Pyoderma gangrenosum (PG)
C	Psoriasis
D	Perianal skin tags

Question 14 Explanation:

Perianal skin tags are found in 75 - 80% of patients with CD, especially those with colon involvement

Question 15

Peripheral arthritis that develops in IBD patients involves which of the following joints ?

A	Small joints of upper & lower extremities
B	Large joints of upper & lower extremities
C	Small joints of upper extremity
D	Small joints of lower extremity

Question 15 Explanation:

Peripheral arthritis of IBD patients is asymmetric, polyarticular and migratory and affects large joints of upper and lower extremities

Question 16

Rheumatologic manifestations of IBD include all except ?

A	Peripheral arthritis
B	Ankylosing spondylitis (AS)
C	Osteopetrosis
D	Sacroiliitis

Question 17

Rheumatologic manifestations of IBD include all except ?

A	Hypertrophic osteoarthropathy
B	Pelvic/femoral osteomyelitis
C	Relapsing polychondritis
D	Costochondritis

Question 18

Which of the following skeletal disease occurs equally in UC and CD ?

A	Peripheral arthritis
B	Ankylosing spondylitis (AS)
C	Sacroiliitis
D	All of the above

Question 18 Explanation:

Symmetric sacroiliitis occurs equally in UC & CD. Peripheral arthritis and ankylosing spondylitis are more common in CD than UC.

Question 19

Ocular manifestations of IBD include all except ?

A	Conjunctivitis
B	Anterior uveitis / iritis
C	Episcleritis
D	Retinitis

Question 19 Explanation:

Ocular manifestations of IBD include conjunctivitis, anterior uveitis/iritis, and episcleritis.

Question 20

Common hepatobiliary manifestations of IBD include all except ?

A	Hepatic steatosis
B	Pancreatitis
C	Cholelithiasis
D	Primary sclerosing cholangitis (PSC)

Question 20 Explanation:

Pancreatitis is a rare extraintestinal manifestation of IBD and results from duodenal fistulas, ampullary CD, gallstones, PSC, autoimmune pancreatitis and primary CD of the pancreas.

Question 21

All are complications of UC except ?

A	Hemorrhage
B	Malignant change
C	Intusucception
D	Polyposis

Question 22

Urologic manifestations of IBD include all except ?

A	Calculi
B	Ureteral obstruction
C	Ileal bladder fistulas
D	Glomerulonephritis

Question 23

Hypercoagulable state in IBD is due to all except ?

A	Reactive thrombocytosis
B	Increased fibrinopeptide A, factor V, VIII & fibrinogen
C	Decreased thromboplastin generation
D	Antithrombin III deficiency

Question 23 Explanation:

In IBD, risk of venous & arterial thrombosis increases even when disease is not active due to abnormalities of platelet-endothelial interaction, hyperhomocysteinemia, alterations in coagulation cascade, impaired fibrinolysis, involvement of tissue factor-bearing microvesicles, disruption of normal coagulation system by autoantibodies, vasculitides and genetic predisposition

Question 24

Cardiopulmonary manifestations of IBD include all except ?

A	Endocarditis / Myocarditis
B	Pleuropericarditis
C	Interstitial lung disease (ILD)
D	Obstructive lung disease

Question 24 Explanation:

In IBD, cardiopulmonary manifestations include endocarditis, myocarditis, pleuropericarditis, & ILD

Question 25

Most common extraintestinal pulmonary complication of IBD is ?

A	ILD
B	Pneumonitis
C	Malignancy
D	Obstructive lung disease

Question 26

Role of sulfasalazine is not clear in which of the following ?

A	Inducing remission in UC
B	Maintaining remission in UC
C	Inducing remission in CD
D	Maintaining remission in CD

Question 26 Explanation:

Sulfasalazine and other 5-ASA agents are effective at inducing and maintaining remission in UC with limited role in inducing remission in CD but no clear role in maintenance of CD. The most convincing evidence for use of sulfasalazine is treatment of active CD involving colon.

Question 27

Name of the bond linking the sulfa and 5-ASA moieties in Sulfasalazine is ?

A	Azo bond
B	Thio bond
C	Tau bond
D	Conn bond

Question 27 Explanation:

Sulfasalazine is broken down in colon by bacterial azo reductases. They cleave the azo bond linking the sulfa and 5-ASA moieties

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See all quizzes of Peptic Ulcer Disease at here:

1.Which of the following can cause proctitis ?
A. Gonorrhea
B. Chlamydia
C. Syphilis
D. All of the above

2. Which of the following can cause watery diarrhea ?
A. Salmonella
B. Shigella
C. C. difficile
D. All of the above

3. Parasitic infections that mimic IBD include all except ?
A. Necator americanus
B. Trichuris trichiura

C. Strongyloides stercoralis
D. Enterobius vermicularis

4. Which of the following IBD patients are at higher risk for
developing extraintestinal manifestations ?
A. IBD with Selective IgA deficiency
B. IBD with granulomas
C. Perianal Crohn’s disease
D. IBD with Turner’s syndrome
5. Patients with inflammatory bowel disease are at risk for ?
A. Primary sclerosing cholangitis
B. Ankylosing spondylitis
C. Psoriasis
D. All of the above

6. Which of the following is false about collagenous colitis ?
A. Increased subepithelial collagen deposition
B. Male to female ratio is 9:1
C. Most patients present in 6th or 7th decades
D. Main symptom is chronic watery diarrhea

7. Which of the following is false about Erythema nodosum (EN)
in IBD ?
A. Correlate with bowel activity
B. Develop after onset of bowel symptoms
C. Concomitant active peripheral arthritis
D. None of the above

8. Which of the following is false about Erythema nodosum ?
A. Erythematous tender nodules
B. 1-5 cm in diameter
C. Found on anterior surface of lower legs and arms
D. None of the above

9. Which of the following is false about Pyoderma gangrenosum
(PG) in IBD ?
A. May occur years before onset of bowel symptoms
B. Independent of the bowel disease
C. Respond poorly to colectomy
D. None of the above

10. Which of the following is false about Pyoderma gangrenosum
(PG) ?
A. Found on dorsal surface of feet and legs
B. Usually begins as a macule
C. May be single or multiple
D. Difficult to treat

11. Dermatologic manifestations of IBD include all except ?
A. Erythema nodosum (EN)
B. Pyoderma gangrenosum (PG)
C. Pyoderma vegetans
D. Erythema marginatum
12. Dermatologic manifestations of IBD include all except ?
A. Pyostomatitis vegetans
B. Alopecia
C. Perianal skin tags
D. Psoriasis
13.Which of the following skin lesions is most frequent in CD ?
A. Erythema nodosum (EN)
B. Pyoderma gangrenosum (PG)
C. Psoriasis
D. Perianal skin tags

14. Peripheral arthritis that develops in IBD patients involves which
of the following joints ?
A. Small joints of upper & lower extremities
B. Large joints of upper & lower extremities
C. Small joints of upper extremity
D. Small joints of lower extremity

15. Rheumatologic manifestations of IBD include all except ?
A. Peripheral arthritis
B. Ankylosing spondylitis (AS)
C. Osteopetrosis
D. Sacroiliitis
16. Rheumatologic manifestations of IBD include all except ?
A. Hypertrophic osteoarthropathy

B. Pelvic/femoral osteomyelitis
C. Relapsing polychondritis
D. Costochondritis
17. Which of the following skeletal disease occurs equally in UC
and CD ?
A. Peripheral arthritis
B. Ankylosing spondylitis (AS)
C. Sacroiliitis
D. All of the above

18. Ocular manifestations of IBD include all except ?
A. Conjunctivitis
B. Anterior uveitis / iritis
C. Episcleritis
D. Retinitis

19. Common hepatobiliary manifestations of IBD include all
except ?
A. Hepatic steatosis
B. Pancreatitis
C. Cholelithiasis
D. Primary sclerosing cholangitis (PSC)

20. All are complications of UC except ?
A. Hemorrhage
B. Malignant change
C. Intusucception
D. Polyposis
21. Urologic manifestations of IBD include all except ?
A. Calculi
B. Ureteral obstruction
C. Ileal bladder fistulas
D. Glomerulonephritis
22. Hypercoagulable state in IBD is due to all except ?
A. Reactive thrombocytosis
B. Increased fibrinopeptide A, factor V, VIII & fibrinogen
C. Decreased thromboplastin generation
D. Antithrombin III deficiency

23. Cardiopulmonary manifestations of IBD include all except ?
A. Endocarditis / Myocarditis
B. Pleuropericarditis
C. Interstitial lung disease (ILD)
D. Obstructive lung disease

24. Most common extraintestinal pulmonary complication of IBD
is ?
A. ILD
B. Pneumonitis
C. Malignancy
D. Obstructive lung disease
25.Role of sulfasalazine is not clear in which of the following ?
A. Inducing remission in UC
B. Maintaining remission in UC
C. Inducing remission in CD
D. Maintaining remission in CD

26. Name of the bond linking the sulfa and 5-ASA moieties in
Sulfasalazine is ?
A. Azo bond
B. Thio bond
C. Tau bond
D. Conn bond

Inflammatory bowel disease

[MCQ] Inflammatory bowel disease- Part 4

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Inflammatory bowel disease- Part 4

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