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HIV / AIDS- Part 1
See all quizzes of HIV / AIDS- Part 1 here:
1 In a HIV-infected individual, AIDS is present if CD4+ T cell count is ?
A. < 200 / μL
B. < 250 / μL
C. < 300 / μL
D. < 350 / μL
2 The earliest documented case of HIV infection in humans was
identified in 1959 in ?
A. Congo
B. Zambia
C. Uganda
D. Zaire
3 AIDS was first reported in which of the following ?
A. British Medical Bulletin
B. Morbidity and Mortality Weekly Report
C. The Lancet
D. Journal of Clinical Virology
4 Who is credited with the discovery of virus that causes AIDS ?
A. Dr. Robert Gallo
B. Dr. David Ho
C. Dr. Clayton A. Buck
D. Dr. Anthony S. Fauci
5 Who is known as “patient zero” by AIDS researchers ?
A. Ryan White
B. Earvin “Magic” Johnson
C. Gaetan Dugas
D. Arthur Ashe
6 Documented HIV infection is Category A, when which of the
following conditions is present ?
Harrison’s 18th Ed. 1507 Table 189-2
A. Asymptomatic HIV infection
B. Persistent generalized lymphadenopathy
C. With accompanying illness/history of acute HIV infection
D. Any of the above
7 Clinical category in asymptomatic HIV infection with CD4+ T cell
count <200/μL is ?
A. A 1
B. A 2
C. A 3
D. Any of the above
8 In Clinical Category A1, CD4+ T cell count is ?
A. > 200 / μL
B. > 300 / μL
C. > 400 / μL
D. > 500 / μL
9 HIV belongs to the subfamily of ?
Harrison’s 18th Ed. 1506
A. Retroviridae
B. Lentiviruses
C. Human metapneumoviruses
D. Coronaviruses
10 Which of the following is false about HIV virus ?
A. RNA virus
B. Cytopathic virus
C. Zoonotic infection
D. None of the above
11 HIV-1 came to humans from ?
A Chimpanzee
B. Sooty mangabey monkeys
C. Rhesus macaque
D. All of the above
12 HIV-2 originated from ?
A Chimpanzee
B. Sooty mangabey monkeys
C. Rhesus macaque
D. All of the above
13 The diameter of mature HIV virion is ?
A. 100 – 120 nm
B. 140 – 160 nm
C. 160 – 180 nm
D. 180 – 200 nm
14 HIV is a ?
A. Acidic pH dependent virus
B. Alkaline pH dependent virus
C, Neutral pH dependent virus
D. pH independent virus
15 The HIV envelope protein is a ?
A. Monomer
B. Dimer
C. Trimer
D. Tetramer
16 Nucleocapsid of HIV virion is ?
A. Spherical
B. Cone-shaped
C. Cylinder-shaped
D. Elliptical-shaped
17 Lipid bilayer of HIV mature virion includes aproximately ?
A. 24 spikes
B. 60 spikes
C. 72 spikes
D. 96 spikes
18 Which are the two major envelope proteins of HIV ?
A. Glycoprotein 120 and glycoprotein 41 subunits
B. Glycoprotein 120 and glycoprotein 39 subunits
C. Glycoprotein 160 and glycoprotein 41 subunits
D. Glycoprotein 160 and glycoprotein 39 subunits
19 The glycoprotein 41 subunit of HIV envelope protein has which
of the following component ?
A. N-terminal hydrophobic domain termed fusion peptide
B. Helical region 1
C. Helical region 2
D. All of the above
20 What percentage of homology exists between HIV-2 DNA and HIV-
1 DNA ?
A. 10 to 20 percent
B. 20 to 40 percent
C. 40 to 60 percent
D. 60 to 80 percent
21 Which of the following statements about HIV-2 is true ?
A. HIV-2 has vpu gene and not vpx gene
B. HIV-2 has vpx gene and not vpu gene
C. HIV-2 has both vpx and vpu gene
D. HIV-2 does not have vpx and vpu gene
22 Which viral-envelope glycoprotein of HIV-1 is required for
attachment of virions to the CD4 cellular receptors ?
A. gp 80
B. gp 100
C. gp 120
D. gp 140
23 Which component of HIV is first inserted into the membrane of
the target cell ?
A. Glycoprotein 41
B. Glycoprotein 24
C. Glycoprotein 120
D. Glycoprotein 160
24 CD4 molecule is a ?
A. 35-kDa protein
B. 45-kDa protein
C. 55-kDa protein
D. 65-kDa protein
25 CD4 molecule is found on the surface of ?
A. A subset of T lymphocytes
B. Monocytes / Macrophages
C. Dendritic / Langerhans cells
D. All of the above
