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Glomerular Diseases- Part 2
See all quizzes of Glomerular Diseases at here:
1.Cryoglobulinemia has which of the following patterns of clinical glomerulonephritis ?
A. Acute Nephritic Syndrome
B. Pulmonary-Renal Syndrome
C. Glomerular Vascular Syndrome
D. All of the above
2. Churg-Strauss syndrome has which of the following patterns of clinical glomerulonephritis ?
A. Acute Nephritic Syndrome
B. Pulmonary-Renal Syndrome
C. Glomerular Vascular Syndrome
D. All of the above
3. Which of the following stains is used to enhance basement membrane structure in renal biopsy ?
A. Hematoxylin and eosin
B. Periodic acid-Schiff (PAS)
C. Jones-methenamine silver
D. Masson’s trichrome
4. By light microscopy, ideally how many glomeruli should be reviewed individually for discrete lesions ?
A. 1
B. 5
C. 10
D. 20
5. ‘Focal glomeulonephritis’ is said to occur when lesion involves what proportion of glomeruli ?
A. < 50 %
B. < 60 %
C. < 70 %
D. < 80 %
6. In renal biopsy, which of the following is an ominous sign of irreversibility and progression to renal failure ?
A. Synechiae
B. Interstitial fibrosis
C. Crescents
D. All of the above
7. Acute nephritic syndromes classically present with ?
A. Hypertension
B. Hematuria
C. Pyuria
D. All of the above
8. Circulating immune-complex formation and deposition within the glomerulus is seen in ?
A. Subacute bacterial endocarditis (SABE)
B. Lupus nephritis
C. Hepatitis-C-related cryoglobulinaemia
D. All of the above
9. Poststreptococcal glomerulonephritis is prototypical for ?
A. Acute endocapillary proliferative glomerulonephritis
B. Mesangiocapillary glomerulonephritis
C. Lobar glomerulonephritis
D. Segmental necrotizing glomerulonephritis
10. Poststreptococcal glomerulonephritis develops how many weeks after streptococcal pharyngitis ?
A. 1 – 3 weeks
B. 2 – 6 weeks
C. 3 – 6 weeks
D. 4 – 8 weeks
11. Poststreptococcal glomerulonephritis due to impetigo develops how many weeks after the skin infection ?
A. 1 – 3 weeks
B. 2 – 6 weeks
C. 3 – 6 weeks
D. 4 – 8 weeks
12. In the first week of poststreptococcal glomerulonephritis, which of the following findings is false ?
A. Depressed total hemolytic complement (CH50)
B. Decreased levels of C3
C. Normal levels of C4
D. None of the above
13. Poststreptococcal glomerulonephritis develops how many days after pharyngitis ?
A. 10 days
B. 20 days
C. 30 days
D. 40 days
14. Poststreptococcal glomerulonephritis develops how many weeks after skin infection ?
A. 1 week
B. 2 weeks
C. 3 weeks
D. 4 weeks
15. “Starry sky” appearance on immunofluorescence microscopy of renal biopsy is seen in ?
A. Acute poststreptococcal glomerulonephritis
B. Lupus nephritis
C. Glomerulonephritis in SLE
D. Goodpasture’s syndrome
16. Lupus nephritis is most severe in ?
A. African-American female adolescents
B. White elderly
C. Australian aboriginals
D. Chinese young male
17. Which of the following glomerulonephritis is more common in female than in male population ?
A. Alport’s Syndrome
B. Goodpasture’s syndrome
C. Lupus nephritis
D. Nail-patella syndrome
18. First name of Goodpasture was ?
A. Albert
B. Ellis
C. Ernest
D. Eric
19. Which of the following is not a basement membrane syndrome ?
A. Alport’s Syndrome
B. Goodpasture’s syndrome
C. Churg-Strauss syndrome
D. Nail-patella syndrome
20. Which of the following is true for ‘anti-GBM disease’ ?
A. Detectable circulating anti-GBM autoantibodies
B. Normal serum complement levels
C. Absent ANCA
D. All of the above
21. Which of the following is true for Goodpasture’s syndrome ?
A. Anti-GBM nephritis
B. Lung hemorrhage
C. Autoimmune disease
D. All of the above
22. Which chain of type IV collagen is the target antigen in Goodpasture’s syndrome ?
A. α1
B. α2
C. α3
D. v4
