I. Start the exam by click the “Start” button
CARBOHYDRATES AND CARBOHYDRATE METABOLISM- Part 9
See all quizzes of CARBOHYDRATES AND CARBOHYDRATE METABOLISM- Part 9 here:
1. The normal resting state of humans, most
of the blood glucose burnt as “fuel” is
consumed by
(A) Liver (B) Brain
(C) Kidneys (D) Adipose tissue
2. A regulator of the enzyme Glycogen
synthase is
(A) Citric acid
(B) 2, 3 bisphosphoglycerate
(C) Pyruvate
(D) GTP
3. Which of the following compound is a
positive allosteric modifier of the enzyme
pyruvate carboxylase?
(A) Biotin (B) Acetyl CoA
(C) Oxaloacetate (D) ATP
4. A specific inhibitor for succinate
dehydrogenase is
(A) Arsinite (B) Melouate
(C) Citrate (D) Cyanide
5. Most of the metabolic pathways are
either anabolic or catabolic. Which of the
following pathways is considered as
“amphibolic” in nature?
(A) Glycogenesis (B) Glycolytic pathway
(C) Lipolysis (D) TCA cycle
6. Transketolase activity is affected in
(A) Biotin deficiency
(B) Pyridoxine deficiency
(C) PABA deficiency
(D) Thiamine deficiency
7. The following metabolic abnormalities
occur in Diabetes mellitus except
(A) Increased plasma FFA
(B) Increased pyruvate carboxylase activate
(C) Decreased lipogenesis
(D) Decreased gluconeogenesis
8. A substance that is not an intermediate
in the formation of D-glucuronic acid from
glucose is
(A) Glucoss-1-p
(B) 6-Phosphogluconate
(C) Glucose-6-p
(D) UDP-Glucose
9. The hydrolysis of Glucose-6-P is catalysed
by a phosphatase that is not formed in
which of the following?
(A) Liver (B) Kidney
(C) Muscle (D) Small intestine
10. An essential for converting Glucose to
Glycogen in Liver is
(A) Lactic acid (B) GTP
(C) CTP (D) UTP
11. Which of the following is a substrate for
aldolase activity in Glycolytic pathway?
(A) Glyceraldehyde-3-p
(B) Glucose-6-p
(C) Fructose-6-p
(D) Fructose1, 6-bisphosphate
12. The ratio that approximates the number
of net molecule of ATP formed per mole
of Glucose oxidized in presence of O2 to
the net number formed in abscence of
O2 is
(A) 4 : 1 (B) 10 : 2
(C) 12 : 1 (D) 18 : 1
13. The “Primaquin sensitivity types of
haemolytic anaemia has been found to
relate to reduced R.B.C activity of which
enzyme?
(A) Pyruvate kinase deficiency
(B) Glucose-6-phosphatase deficiency
(C) Glucose-6-p dehydrogenase deficiency
(D) Hexokinase deficiency
14. Which of the following hormones is not
involved in carbohydrate metabolism?
(A) Cortisol (B) ACTH
(C) Glucogen (D) Vasopressin
15. Dehydrogenases involved in HMP shunt
are specific for
(A) NADP+ (B) NAD+
(C) FAD (D) FMN
16. Which of the following enzymes in Glycolytic
pathway is inhibited by fluoride?
(A) Glyceraldehyde-3-p dehydrogenase
(B) Phosphoglycerate kinase
(C) Pyruvate kinase
(D) Enolase
17. Out of 24 mols of ATP formed in TCA cycle,
2 molecules of ATP can be formed at
“substrate level” by which of the
following reaction ?
(A) Citric acid→ Isocitric acid
(B) Isocitrate→ Oxaloacetate
(C) Succinic acid→ Fumarate
(D) Succinylcat→ Succinic acid
18. Which of the following statements
regarding T.C.A cycle is true?
(A) It is an anaerobic process
(B) It occurs in cytosol
(C) It contains no intermediates for Gluconeogenesis
(D) It is amphibolic in nature
19. An allosteric enzyme responsible for
controlling the rate of T.C.A cycle is
(A) Malate dehydrogenase
(B) Isocitrate dehydrogenase
(C) Fumarase
(D) Aconitase
20. The glycolysis is regulated by
(A) Hexokinase (B) Phosphofructokinase
(C) Pyruvate kinase (D) All of these
21. How many ATP molecules will be required
for conversion of 2-molecules of Lactic acid
to Glucose?
(A) 2 (B) 4
(C) 8 (D) 6
22. Which of the following enzyme is not
involved in HMP shunt?
(A) Glyceraldehyde-3-p dehydrogenase
(B) Glucose-6-p-dehydrogenase
(C) Transketolase
(D) Phosphogluconate dehydrogenase
23. In presence of the following cofactor,
pyruvate carboxylase converts pyruvate
to oxaloacetate:
(A) ATP, Protein and CO2
(B) CO2 and ATP
(C) CO2
(D) Protein
24. For conversion of oxaloacetate to
phosphoenol pyruvate, high energy
molecule is required in the form of
(A) GTP only (B) ITP only
(C) GTP (or) ITP (D) None of these
25. If the more negative standard reduction
potential of a redox pair, the greater the
tendency to
(A) To lose electrons
(B) To gain electrons
(C) To lose/gain electrons
(D) To lose and gain electrons
26. Electron transport and phosphorylation
can be uncoupled by compounds that
increase the permeability of the inner
mitochondrial membrane to
(A) Electrons (B) Protons
(C) Uncouplers (D) All of these
27. The more positive the E0, the greater the
tendency of the oxidant member of that
pair to
(A) Lose electrons
(B) Gain electrons
(C) Lose (or) gain electrons
(D) Lose and gain electrons
28. The standard free energy of hydrolysis
of terminal phosphate group of ATP is
(A) –7,300 cal/mol (B) –8,300 cal/mol
(C) 10,000 cal/mol (D) +7,300 cal/mol
29. The transport of a pair of electrons from
NADH to O2 via the electron transport
chain produces
(A) –52,580 cal (B) –50,580 cal
(C) 21,900 cal (D) +52,580 cal
