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Disorders of the Testes and Male Reproductive System- Part 4
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Disorders of the Testes and Male Reproductive System- Part 1| Disorders of the Testes and Male Reproductive System- Part 2|Disorders of the Testes and Male Reproductive System- Part 3|Disorders of the Testes and Male Reproductive System- Part 4|Disorders of the Testes and Male Reproductive System- Part 5|Disorders of the Testes and Male Reproductive System- Part 6
1. Mechanism of marijuana-induced hypogonadism is ?
A. Androgen deficiency
B. Decreased GnRH secretion
C. Cytokine and/or glucocorticoid effects
D. All of the above
2. Which of the following is false in obesity ?
A. Decrease in SHBG levels
B. Normal free testosterone levels
C. Higher estradiol levels
D. None of the above
3. Which of the following is a cause of hypogonadism ?
A. Pituitary adenoma
B. Craniopharyngioma
C. Hemochromatosis
D. All of the above
4. Hypogonadism can be caused by ?
A. Anorchia syndrome
B. Myotonic dystrophy
C. Klinefelter syndrome
D. All of the above
5. The occurrence of Klinefelter syndrome is ?
A. 1 in 1000 live-born males
B. 1 in 10000 live-born males
C. 1 in 100000 live-born males
D. 1 in 1000000 live-born males
6. Which of the following is a feature of Klinefelter syndrome ?
A. Gynecomastia
B. Decreased Testosterone
C. Increased estradiol
D. All of the above
7. Men with Klinefelter syndrome are at a reduced risk of ?
A. Breast cancer
B. Non-Hodgkin’s lymphoma
C. Lung cancer
D. Prostate cancer
8. Genotype in classic form of Klinefelter syndrome is ?
A. 47,XXY
B. 46,XY
C. 47, XXY
D. 48,XXYY
9. Hormone profile in Klinefelter syndrome includes all except ?
A. Increased FSH
B. Increased LH
C. Decreased estradiol
D. Decreased testosterone
10. Clinical features of Klinefelter syndrome includes all except ?
A. Gynecomastia
B. Normal sized testes
C. Infertility
D. Eunuchoid features
11. Which of the following is the most frequent karyotype in Turner
syndrome (TS) ?
A. 45,X
B. 46,XX
C. 45,X
D. X fragments
12. Turner syndrome is characterized by all except ?
A. Phenotypic females
B. Short stature
C. Primary amenorrhea
D. Gynecomastia
13. In an adult female with Turner syndrome, which of the following
is not found ?
A. Hypertension
B. Osteoporosis
C. Chronic pancreatitis
D. Inflammatory bowel disease
14. Gonadal dysgenesis & renal dysfunction occurs due to mutations
in which of the following genes ?
A. WT1
B. SF1
C. SOX9
D. All of the above
15. Gonadal dysgenesis & primary adrenal failure occurs due to
mutations in which of the following genes ?
A. WT1
B. SOX9
C. SF1
D. All of the above
16. Gonadal dysgenesis & campomelic dysplasia occurs due to
mutations in which of the following genes ?
A. WT1
B. SOX9
C. SF1
D. All of the above
17. Viral orchitis may be caused by ?
A. Mumps virus
B. Echovirus
C. Lymphocytic choriomeningitis virus
D. All of the above
18. Orchitis occurs in what percentage of adult men with mumps ?
A. 10 %
B. 25 %
C. 50 %
D. 75 %
19. At what dose of radiation, oligospermia or azoospermia develops ?
A. 20 rad
B. 40 rad
C. 60 rad
D. 80 rad
20. Which of the following inhibits testosterone synthesis ?
A. Spironolactone
B. Ketoconazole
C. Marijuana
D. All of the above
21. Which of the following blocks androgen action ?
A. Spironolactone
B. Ketoconazole
C. Marijuana
D. All of the above
22. Pituitary tumors in Carney complex secrete which of the following
hormones ?
A. GH
B. Prolactin
C. ACTH
D. Vasopressin
23. Which of the following tumors occur in Carney complex ?
A. Testicular
B. Adrenal
C. Pituitary
D. All of the above
24. In Carney syndrome, mutation occurs in which of the following
gene ?
A. PRKA1A
B. PRKA1B
C. PRKA1C
D. PRKA1D
25. Which of the following is a feature of Carney syndrome ?
A. Myxoma
B. Colour blindness
C. Flat foot
D. Hypothyroidism
26. Which of the following is not a feature of Peutz-Jeghers syndrome ?1o
A. Mucocutaneous pigmentation
B. Intestinal polyps
C. Leydig cell tumors in men
D. Ovarian sex cord stromal tumors