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Glomerular Diseases- Part 1
See all quizzes of Glomerular Diseases at here:
1. Number of glomerular capillary tufts in the two human kidneys is about ?
A. 0.6 million
B. 1.2 million
C. 1.8 million
D. 2.4 million
2. Pores in the glomerular basement membrane (GBM) and slit pore membranes have a radius of ?
A. 2 nm
B. 4 nm
C. 6 nm
D. 8 nm
3. Which of the following is instrumental in reclaiming filtered albumin along the proximal tubule ?
A. Crucin
B. Optimin
C. Megalin
D. Reglin
4. Congenital nephrotic syndrome occurs due to mutations in ?
A. PROP-1
B. NPHS1
C. PAX-8
D. PIT-1
5. Glomerulonephritis refers to inflammation of ?
A. Glomerular capillaries
B. Glomerular arterioles
C. Glomerular basement membrane (GBM)
D. All of the above
6. In glomerulonephritis, cytokines & proteases damage which of the following ?
A. Mesangium
B. Capillaries
C. GBM
D. All of the above
7. Which of the following is associated with immune deposits along the GBM ?
A. Poststreptococcal glomerulonephritis
B. Lupus nephritis
C. Idiopathic membranous nephritis
D. All of the above
8. Persistent glomerulonephritis that worsens renal function is always accompanied by ?
A. Interstitial nephritis
B. Renal fibrosis
C. Tubular atrophy
D. All of the above
9. Renal failure in glomerulonephritis best correlates histologically with the appearance of ?
A. Tubulointerstitial nephritis
B. Papillary necrosis
C. Cystic kidney disease
D. All of the above
10. Cause of microscopic hematuria is ?
A. Interstitial nephritis
B. Papillary necrosis
C. Cystic kidney diseases
D. All of the above
11. Normal 24-hour urine protein is ?
A. < 30 mg/day
B. < 100 mg/day
C. < 150 mg/day
D. < 300 mg/day
12. Albumin comprises what percentage of total proteins excreted in the urine ?
A. 10 – 30 %
B. 20 – 50 %
C. 30 – 70 %
D. 40 – 90 %
13. Sustained isolated proteinuria is found in ?
A. Diabetic nephropathy
B. Mesangioproliferative glomerulonephritis
C. FSGS
D. All of the above
14. Orthostatic proteinuria is evident only in ?
A. Upright position
B. Recumbent position
C. Sitting position
D. Lateral position
15. Functional proteinuria refers to ?
A. Proteinuria in females
B. Proteinuria during fever, emotional stress
C. Proteinuria in UTI
D. Proteinuria in upright posture
16. Which of the following can present with gross hematuria ?
A. Focal segmental glomerulosclerosis
B. Mesangioproliferative glomerulonephritis
C. IgA nephropathy
D. Subacute bacterial endocarditis
17. Which of the following can present with gross hematuria ?
A. Henoch-Schönlein purpura
B. Antiphospholipid syndrome
C. Sickle cell disease
D. Nail-patella syndrome
18. Asymptomatic hematuria is due to ?
A. IgA nephropathy (Berger’s disease)
B. Thin basement membrane (TBM) disease
C. Alport’s syndrome
D. All of the above
19. Which of the following is false about a ‘crescent’ ?
A. Half-moon-shaped collection of cells in Bowman’s space
B. Composed of proliferating parietal epithelial cells and infiltrating macrophages
C. Crescentic glomerulonephritis is also called rapidly progressive glomerulonephritis
D. None of the above
20. Which of the following does not present as rapidly progressive glomerulonephritis (RPGN) ?
A. Poststreptococcal glomerulonephritis
B. Subacute bacterial endocarditis
C. Wegener’s granulomatosis
D. Henoch-Schönlein purpura
21. Which of the following does not present as rapidly progressive glomerulonephritis (RPGN) ?
A. Poststreptococcal glomerulonephritis
B. Mesangioproliferative glomerulonephritis
C. Membranoproliferative glomerulonephritis
D. Lupus nephritis
22. Henoch-Schönlein purpura has which of the following patterns of clinical glomerulonephritis ?
A. Acute Nephritic Syndrome
B. Pulmonary-Renal Syndrome
C. Glomerular Vascular Syndrome
D. All of the above
23. Wegener’s granulomatosis has which of the following patterns of clinical glomerulonephritis ?
A. Acute Nephritic Syndrome
B. Pulmonary-Renal Syndrome
C. Glomerular Vascular Syndrome
D. All of the above
